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TX 1877

Known as: TX-1877, TX1877 
 
National Institutes of Health

Papers overview

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2018
2018
Background/Aim: Sugar molecules are often used as a tool to structurally modify chemical compounds. The features of synthesized… Expand
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2009
2009
PurposeIt is well known that hypoxic milieu is the primary cancer environment. Therefore, tumor hypoxia is considered to be a… Expand
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2008
2008
Tumor hypoxia has been considered to be a potential therapeutic target, because hypoxia is a common feature of solid tumors and… Expand
2008
2008
We have designed sugar-hybrid TX-1877 derivatives conjugated with sugar moieties including beta-glucose (beta-Glc), beta… Expand
2005
2005
We investigated in the current study the effect of TX‐1877, a bifunctional hypoxic cell radiosensitizer, in augmenting anticancer… Expand
2002
2002
The biochemical effects of the 2-nitroimidazole hypoxic cell radiosensitizers KIN-804, KIN-806, and their analogues KIN-844 and… Expand
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2001
2001
We designed, based on the molecular orbital (MO) calculation, synthesized, and evaluated the biological activities of the new… Expand
1998
1998
PURPOSE 2-Nitroimidazole acetamide TX-1877 and its derivatives (TX-1877 analogs) were designed, synthesized, and evaluated by… Expand