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Clinical Significance of Histone Deacetylase 1 Expression in Patients with Hepatocellular Carcinoma
TLDR
High HDAC1 expression might have an important role in the aggressiveness and cell dedifferentiation, and its expression status may be a useful biomarker for predicting the outcome of the patients with HCC. Expand
Transcriptional repressor snail and progression of human hepatocellular carcinoma.
TLDR
The data indicate that Snail both down-regulates E-cadherin expression and promotes the invasion in human HCC. Expand
Prognosis of recurrent hepatocellular carcinoma: a 10-year surgical experience in Japan.
TLDR
The establishment of a follow-up system, including an examination for extrahepatic recurrence, and the development of an effective method of adjuvant chemotherapy are required to obtain better treatment results. Expand
Bile Leakage After Hepatic Resection
TLDR
Patients with bile leakage from the hepatic hilum and postoperative uncontrollable ascites tend to have a poor prognosis, especially when a high-risk surgical procedure is performed in patients with liver cirrhosis, and more careful surgical procedures and use of an intraoperative biles leakage test are recommended. Expand
Laparoscopic hepatectomy for hepatocellular carcinoma
TLDR
Laroscopic hepatectomy can be a new alternative for treatment of cirrhotic patients with HCC when patients are strictly selected and results show that it has resulted in a better short-term outcome after surgery than conventional open hepATEctomy. Expand
The Kampo medicine, Goshajinkigan, prevents neuropathy in patients treated by FOLFOX regimen
TLDR
The Kampo medicine, Goshajinkigan, is useful in preventing neuropathy in non-resectable or recurrent colorectal cancer patients treated with a FOLFOX regimen and there were no differences in adverse effects except for peripheral neuropathy and influence on tumor response. Expand
Classification of biliary tract cancers established by the Japanese Society of Hepato‐Biliary‐Pancreatic Surgery: 3rd English edition
TLDR
The 3rd English edition of the Japanese classification of biliary tract cancers was released approximately 10 years after the 5th Japanese edition and the 2nd English edition, and principally adopted the 7th edition of staging system developed by the International Union Against Cancer and the American Joint Committee on Cancer. Expand
Repeat hepatectomy is the most useful treatment for recurrent hepatocellular carcinoma.
TLDR
Repeat hepatectomy is the preferred treatment offering a hope of long-term survival for patients with recurrent HCC as long as liver function is sufficient; thus early detection of recurrence should be ensured. Expand
Rab13 Mediates the Continuous Endocytic Recycling of Occludin to the Cell Surface*
TLDR
Results suggest that Rab13 specifically mediates the continuous endocytic recycling of occludin to the cell surface in both fibroblastic and epithelial cells. Expand
Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy
TLDR
TJ-107 appears to have an acceptable safety margin and a promising effect in delaying the onset of grade 2 or greater OPN without impairing FOLFOX efficacy. Expand
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