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Transcriptional repressor snail and progression of human hepatocellular carcinoma.
PURPOSE Snail protein is a suppressive transcriptional factor of E-cadherin that mediates cell-to-cell adhesion, tumor progression, and metastases. We explored the expression and function of SnailExpand
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Clinical Significance of Histone Deacetylase 1 Expression in Patients with Hepatocellular Carcinoma
Objective: Histone deacetylases (HDACs) play an important role in chromatin remodeling, gene repression and regulating cell cycle progression and differentiation. This study was designed to clarifyExpand
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MR cholangiopancreatographic differentiation of benign and malignant intraductal mucin-producing tumors of the pancreas.
OBJECTIVE The purpose of this study was to establish MR cholangiopancreatographic criteria for discriminating benign from malignant intraductal mucin-producing tumors of the pancreas. MATERIALS ANDExpand
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A Pancreaticoduodenectomy Risk Model Derived From 8575 Cases From a National Single-Race Population (Japanese) Using a Web-Based Data Entry System: The 30-Day and In-hospital Mortality Rates for
Objective:To create a mortality risk model after pancreaticoduodenectomy (PD) using a Web-based national database system. Background:PD is a major gastroenterological surgery with relatively highExpand
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The Kampo medicine, Goshajinkigan, prevents neuropathy in patients treated by FOLFOX regimen
BackgroundOxaliplatin is now considered a standard treatment for advanced or unresectable colorectal cancer, but its main dose-limiting toxicity is sensory neuropathy. The OPTIMOX (stop and go)Expand
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Sequential hemodynamic change in hepatocellular carcinoma and dysplastic nodules: CT angiography and pathologic correlation.
OBJECTIVE The purpose of this study was to clarify the hemodynamic changes associated with hepatocarcinogenesis using CT angiography. MATERIALS AND METHODS Eighty-six hepatocellular lesions wereExpand
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A comparison of the surgical outcomes among patients with HBV-positive, HCV-positive, and non-B non-C hepatocellular carcinoma: a nationwide study of 11,950 patients.
OBJECTIVE To compare the prognostic factors and outcomes after hepatic resection among patients with hepatitis B virus (HBV)-positive, hepatitis C virus (HCV)-positive, and negative for hepatitis BExpand
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Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy
PurposeOxaliplatin-induced peripheral neurotoxicity (OPN) is frequent and potentially severe, but successful treatment of this condition is still an unmet clinical need. We aimed to determine whetherExpand
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A Risk Model for Esophagectomy Using Data of 5354 Patients Included in a Japanese Nationwide Web-Based Database
Objective:This study aimed to create a risk model of mortality associated with esophagectomy using a Japanese nationwide database. Methods:A total of 5354 patients who underwent esophagectomy in 713Expand
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Role of Expression of Focal Adhesion Kinase in Progression of Hepatocellular Carcinoma
Purpose: Although hepatocellular carcinoma (HCC) is the most common cancer of the human liver, the mechanisms that regulate HCC development and progression remain unclear. The aim of this study wasExpand
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