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AZD9164

 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
ABSTRACT Introduction: Long acting muscarinic receptor antagonists (LAMA) reverse airflow obstruction by antagonizing para… Expand
2016
2016
INTRODUCTION Pharmacokinetic-pharmacodynamic (PKPD) modelling can improve safety assessment, but few PKPD models describing drug… Expand
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Review
2014
Review
2014
BackgroundAZD9164 has demonstrated potential as an inhaled, long-acting, muscarinic antagonist (LAMA) bronchodilator. However, in… Expand
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2013
2013
There is still a need for new agents which improve upon the therapeutic index of tiotropium, the current standard of care for… Expand
2012
2012
A key challenge in the development of robust bioanalytical methods, for the determination of drug analyte in human urine samples… Expand
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2011
2011
The optimization of a new series of muscarinic M(3) antagonists is described, leading to the identification of AZD9164 which was… Expand