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Piperidines
Known as:
Piperidines [Chemical/Ingredient]
A family of hexahydropyridines.
National Institutes of Health
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1-methyl-4-phenyl-4-hydroxypiperidine
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349U85
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Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
A single step approach to piperidines via Ni-catalyzed β-carbon elimination.
Puneet Kumar
,
J. Louie
Organic Letters
2012
Corpus ID: 7927049
An easy and expeditious route to substituted piperidines is described. A Ni-phosphine complex was used as catalyst for [4 + 2…
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2011
2011
Synthesis, pharmacological activity and structure affinity relationships of spirocyclic σ(1) receptor ligands with a (2-fluoroethyl) residue in 3-position.
Eva Grosse Maestrup
,
C. Wiese
,
D. Schepmann
,
P. Brust
,
B. Wünsch
Bioorganic & Medicinal Chemistry
2011
Corpus ID: 20668032
Highly Cited
2010
Highly Cited
2010
Enantio- and diastereoselective synthesis of piperidines by coupling of four components in a "one-pot" sequence involving diphenylprolinol silyl ether mediated Michael reaction.
Tatsuya Urushima
,
D. Sakamoto
,
H. Ishikawa
,
Y. Hayashi
Organic Letters
2010
Corpus ID: 22724148
An efficient, asymmetric, four-component, one-pot synthesis of highly substituted piperidines with excellent diastereo- and…
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Highly Cited
2010
Highly Cited
2010
Preparation of enantiopure substituted piperidines containing 2-alkene or 2-alkyne chains: application to total syntheses of natural quinolizidine-alkaloids.
Guolin Cheng
,
Xinyan Wang
,
Deyong Su
,
H. Liu
,
Fei Liu
,
Yuefei Hu
Journal of Organic Chemistry
2010
Corpus ID: 34996858
A general method for the preparation of enantiopure 2-alkene- or 2-alkyne-containing chain substituted piperidines was…
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Highly Cited
2009
Highly Cited
2009
Catalytic asymmetric synthesis of piperidines from pyrrolidine: concise synthesis of L-733,060.
J. Bilke
,
S. Moore
,
P. O’Brien
,
J. Gilday
Organic Letters
2009
Corpus ID: 29094280
Catalytic asymmetric deprotonation-aldehyde trapping-ring expansion from a 5- to a 6-ring delivers a concise route to each…
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Highly Cited
2009
Highly Cited
2009
Formal alkyne aza-prins cyclization: gold(I)-catalyzed cycloisomerization of mixed N,O-acetals generated from homopropargylic amines to highly substituted piperidines.
Cheoljae Kim
,
H. Bae
,
+4 authors
Y. Rhee
Journal of the American Chemical Society
2009
Corpus ID: 197275577
A new gold(I)-catalyzed cycloisomerization to access highly substituted piperidines has been developed. By combining a…
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2009
2009
The regio- and stereoselective synthesis of trans-2,3-dihydropyridine N-oxides and piperidines.
Hans F. Andersson
,
M. Gustafsson
,
D. Boström
,
R. Olsson
,
F. Almqvist
Angewandte Chemie
2009
Corpus ID: 29912831
Reactivity N-Own: Pyridine N-oxides can be used for the complete regio- and stereoselective synthesis of trans-substituted…
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Highly Cited
2009
Highly Cited
2009
An efficient synthesis of 2- and 2,6-substituted piperidines using Pd(II)-catalyzed 1,3-chirality transfer reaction.
Sudhir M. Hande
,
N. Kawai
,
J. Uenishi
Journal of Organic Chemistry
2009
Corpus ID: 20650542
An efficient and general method for 2- and 2,6-substituted piperidine syntheses using Pd(II)-catalyzed 1,3-chirality transfer…
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Highly Cited
2006
Highly Cited
2006
Chiral NMR discrimination of piperidines and piperazines using (18-crown-6)-2,3,11,12-tetracarboxylic acid.
Ann E Lovely
,
T. Wenzel
Journal of Organic Chemistry
2006
Corpus ID: 12438759
Enantiomeric discrimination is observed in the (1)H and (13)C NMR spectra of piperidines and piperazines in the presence of…
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Highly Cited
2001
Highly Cited
2001
Intramolecular Mannich reaction in the asymmetric synthesis of polysubstituted piperidines: concise synthesis of the dendrobate alkaloid (+)-241D and its C-4 epimer.
F. A. Davis
,
B. Chao
,
A. Rao
Organic Letters
2001
Corpus ID: 11753490
[reaction: see text] The intramolecular Mannich reaction of delta-amino beta-keto esters with aldehydes and ketones is a new…
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