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Piperidines

Known as: Piperidines [Chemical/Ingredient] 
A family of hexahydropyridines.
National Institutes of Health

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1-methyl-4-phenyl-4-hydroxypiperidine3'-iodobenzovesamicol349U854-astato-N-piperidinoethylbenzamide

Papers overview

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Highly Cited
2012
Highly Cited
2012
A single step approach to piperidines via Ni-catalyzed β-carbon elimination.
An easy and expeditious route to substituted piperidines is described. A Ni-phosphine complex was used as catalyst for [4 + 2… 
2011
2011
Synthesis, pharmacological activity and structure affinity relationships of spirocyclic σ(1) receptor ligands with a (2-fluoroethyl) residue in 3-position.
Highly Cited
2010
Highly Cited
2010
Enantio- and diastereoselective synthesis of piperidines by coupling of four components in a "one-pot" sequence involving diphenylprolinol silyl ether mediated Michael reaction.
An efficient, asymmetric, four-component, one-pot synthesis of highly substituted piperidines with excellent diastereo- and… 
Highly Cited
2010
Highly Cited
2010
Preparation of enantiopure substituted piperidines containing 2-alkene or 2-alkyne chains: application to total syntheses of natural quinolizidine-alkaloids.
A general method for the preparation of enantiopure 2-alkene- or 2-alkyne-containing chain substituted piperidines was… 
Highly Cited
2009
Highly Cited
2009
Catalytic asymmetric synthesis of piperidines from pyrrolidine: concise synthesis of L-733,060.
Catalytic asymmetric deprotonation-aldehyde trapping-ring expansion from a 5- to a 6-ring delivers a concise route to each… 
Highly Cited
2009
Highly Cited
2009
Formal alkyne aza-prins cyclization: gold(I)-catalyzed cycloisomerization of mixed N,O-acetals generated from homopropargylic amines to highly substituted piperidines.
A new gold(I)-catalyzed cycloisomerization to access highly substituted piperidines has been developed. By combining a… 
2009
2009
The regio- and stereoselective synthesis of trans-2,3-dihydropyridine N-oxides and piperidines.
Reactivity N-Own: Pyridine N-oxides can be used for the complete regio- and stereoselective synthesis of trans-substituted… 
Highly Cited
2009
Highly Cited
2009
An efficient synthesis of 2- and 2,6-substituted piperidines using Pd(II)-catalyzed 1,3-chirality transfer reaction.
An efficient and general method for 2- and 2,6-substituted piperidine syntheses using Pd(II)-catalyzed 1,3-chirality transfer… 
Highly Cited
2006
Highly Cited
2006
Chiral NMR discrimination of piperidines and piperazines using (18-crown-6)-2,3,11,12-tetracarboxylic acid.
Enantiomeric discrimination is observed in the (1)H and (13)C NMR spectra of piperidines and piperazines in the presence of… 
Highly Cited
2001
Highly Cited
2001
Intramolecular Mannich reaction in the asymmetric synthesis of polysubstituted piperidines: concise synthesis of the dendrobate alkaloid (+)-241D and its C-4 epimer.
[reaction: see text] The intramolecular Mannich reaction of delta-amino beta-keto esters with aldehydes and ketones is a new… 
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