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Muscular exercise can cause highly pathological liver function tests in healthy men.
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT The occurrence of idiosyncratic drug hepatotoxicity is a major problem in all phases of clinical drug development and the leading cause of postmarketingExpand
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Formoterol for maintenance and as-needed treatment of chronic obstructive pulmonary disease.
Formoterol is a long-acting beta2-agonist with a rapid onset of effect in patients with chronic obstructive pulmonary disease (COPD), making it potentially suitable for both maintenance and as-neededExpand
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Formoterol as relief medication in asthma: a worldwide safety and effectiveness trial
The aim of the study was to compare the safety and effectiveness of as-needed formoterol with salbutamol in a large international real-life asthma study. Children and adults (n=18,124) wereExpand
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Effects of formoterol and ipratropium bromide in COPD: a 3-month placebo-controlled study
The aim of this study was to compare the effects of formoterol, ipratropium bromide and a placebo on walking distance, lung function, symptoms and quality of life (QoL) in chronic obstructiveExpand
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Immunological findings in blood and bronchoalveolar lavage fluid in chronic bronchitis patients with recurrent infectious exacerbations.
Bronchial infections are common in smokers and seem to be related to the presence of chronic bronchitis (CB). Why only some smokers develop repeated bronchial infections is not known. The aim of thisExpand
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Formoterol (OXIS) Turbuhaler as a rescue therapy compared with salbutamol pMDI plus spacer in patients with acute severe asthma.
Formoterol has a similar onset of effect to salbutamol but a prolonged duration of action. However, the relative efficacy of the two drugs in acute severe asthma is not known. This double-blind,Expand
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Effects of a dual CCR3 and H1-antagonist on symptoms and eosinophilic inflammation in allergic rhinitis
BackgroundThe CC-chemokine receptor-3 (CCR3) has emerged as a target molecule for pharmacological intervention in allergic inflammation.ObjectiveTo examine whether a dual CCR3 and H1-receptorExpand
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Relative systemic dose potency and tolerability of inhaled formoterol and salbutamol in healthy subjects and asthmatics
AbstractObjectives: To compare the relative systemic dose potency and tolerability of inhaled formoterol and salbutamol and to describe elimination of formoterol, particularly any enantioselectivity.Expand
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Exposure of infants to budesonide through breast milk of asthmatic mothers.
BACKGROUND Maintenance treatment with inhaled corticosteroids is often required for asthmatic nursing women. Data on the transfer of inhaled corticosteroids from plasma to breast milk and theExpand
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Acute relief of exercise-induced bronchoconstriction by inhaled formoterol in children with persistent asthma.
STUDY OBJECTIVE To compare the acute bronchodilatory effect of the long-acting beta2-agonist formoterol against the short-acting beta2-agonist (SABA) terbutaline during exercise-inducedExpand
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