Quinuclidines

Known as: Quinuclidines [Chemical/Ingredient], quinuclidine 
 

Topic mentions per year

Topic mentions per year

1951-2018
010203019512017

Papers overview

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2007
2007
There is an urgent need for the development of new drugs for the treatment of tropical parasitic diseases such as Chagas' disease… (More)
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2007
2007
The biosynthesis of sterols is a major route for the development of antitrypanosomals. Squalene synthase (SQS) catalyzes the… (More)
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2007
2007
The alpha7 subtype of the neuronal nicotinic acetylcholine receptors (nAChRs) was targeted for the design of selective agonists… (More)
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2006
2006
OBJECTIVES To study the antiproliferative effects of ER119884 and E5700, two quinuclidine-based inhibitors of squalene synthase… (More)
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Highly Cited
2005
Highly Cited
2005
A library of benzamides was tested for alpha7 nicotinic acetylcholine receptor (nAChR) agonist activity using a chimeric receptor… (More)
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2004
2004
Squalene synthase inhibitors have the potential to be superior hypocholesterolemic agents. A series of quinuclidine derivatives… (More)
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2003
2003
The reactivity of a variety of quinuclidine-based catalysts in the Baylis-Hillman reaction has been examined, and a… (More)
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1999
1999
Transmembrane domain 6 of the muscarinic acetylcholine (ACh) receptors is important in ligand binding and in the conformational… (More)
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1997
1997
1. Some nicotinic antagonists (piperidine and quinuclidine derivatives and bis-quaternary compounds) protect early embryos of the… (More)
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1991
1991
Two members of a new class of non-peptide antagonists of substance P, (+-)-cis-3-(2-methoxybenzylamino)-2-benzhydrylquinuclidine… (More)
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