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A lead quinuclidine-based nicotinic ligand (EQA) served as the basis for the design of novel compounds. A new series… Expand The chemoselective α-iodination of various simple and multi-functionalised acrylic esters is efficiently accomplished by a Morita… Expand An efficient method for the solid phase synthesis of allylic alcohols via the Baylis-Hillman reaction has been developed. In the… Expand A method based on the coupling of capillary electrophoresis with mass spectrometry (CE/MS) was developed for the monitoring of 3… Expand 1-Azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(1-iodo-1-propen-3-yl)- alpha-phenylacetate (IQNP, 1), is a highly selective… Expand In response to the scheduled destruction of U.S. military stockpiles of the hallucinogenic agent 3-quinuclidinyl benzilate (QNB… Expand All of the optical isomers of the muscarinic antagonists 3-(1-azabicyclo[2.2.2]octyl) alpha-hydroxy-alpha,alpha-diphenylacetate… Expand Abstract Resolution of (±)3-quinuclidinol into its enantiomers was obtained, at relatively high yield, based on the… Expand The preparation of R-(−)-3-quinuclidinol and its acetate ester is reported. These compounds, together with their racemates, were… Expand