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SphK1 and SphK2, Sphingosine Kinase Isoenzymes with Opposing Functions in Sphingolipid Metabolism*
The results demonstrate that SphK1 and SphK2 have opposing roles in the regulation of ceramide biosynthesis and suggest that the location of sphingosine 1-phosphate production dictates its functions.
ABO3, a WRKY transcription factor, mediates plant responses to abscisic acid and drought tolerance in Arabidopsis.
An ABA overly sensitive mutant, abo3, which is disrupted by a T-DNA insertion in At1g66600 encoding a WRKY transcription factor AtWRKY63 is isolated, uncovering an important role for a WR KY transcription factor in plant responses to ABA and drought stress.
R-Drop: Regularized Dropout for Neural Networks
- Xiaobo Liang, Lijun Wu, Tie-Yan Liu
- Computer ScienceNeural Information Processing Systems
- 28 June 2021
A simple consistency training strategy to regularize dropout, namely R-Drop, which forces the output distributions of different sub models gen-erated by dropout to be consistent with each other.
Optimizing Dense Retrieval Model Training with Hard Negatives
- Jingtao Zhan, Jiaxin Mao, Yiqun Liu, Jiafeng Guo, M. Zhang, Shaoping Ma
- Computer ScienceAnnual International ACM SIGIR Conference on…
- 16 April 2021
This work theoretically investigates different training strategies for DR models and tries to explain why hard negative sampling performs better than random sampling, and proposes two training strategies named a Stable Training Al algorithm for dense Retrieval (STAR) and a query-side training Algorithm for Directly Optimizing Ranking pErformance (ADORE), respectively.
The effects of trust and coercive power on supplier integration
The ER–Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis
A systematic membrane isolation scheme is developed to identify the endoplasmic reticulum–Golgi intermediate compartment (ERGIC) as a primary membrane source both necessary and sufficient to trigger LC3 lipidation in vitro.
Effects of feedstock type, production method, and pyrolysis temperature on biochar and hydrochar properties
Psychological symptoms among frontline healthcare workers during COVID-19 outbreak in Wuhan
Hydrogen peroxide modification enhances the ability of biochar (hydrochar) produced from hydrothermal carbonization of peanut hull to remove aqueous heavy metals: Batch and column tests
PROPAGATION OF SOLAR ENERGETIC PARTICLES IN THREE-DIMENSIONAL INTERPLANETARY MAGNETIC FIELDS: IN VIEW OF CHARACTERISTICS OF SOURCES
In this paper, a model of solar energetic particle (SEP) propagation in the three-dimensional Parker interplanetary magnetic field is calculated numerically. We study the effects of the different…