• Publications
  • Influence
Clinical deterioration in patients with idiopathic pulmonary fibrosis: causes and assessment.
Patients with idiopathic pulmonary fibrosis (IPF) inevitably experience declines in functional status that are most frequently due to progressive pulmonary fibrosis. However, the cause of theExpand
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A Comprehensive Care Management Program to Prevent Chronic Obstructive Pulmonary Disease Hospitalizations
BACKGROUND Improving a patient's ability to self-monitor and manage changes in chronic obstructive pulmonary disease (COPD) symptoms may improve outcomes. OBJECTIVE To determine the efficacy of aExpand
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Oxygen therapy for patients with COPD: current evidence and the long-term oxygen treatment trial.
Long-term use of supplemental oxygen improves survival in patients with COPD and severe resting hypoxemia. However, the role of oxygen in symptomatic patients with COPD and more moderate hypoxemia atExpand
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Pulmonary hypertension associated with COPD
  • J. Elwing, R. Panos
  • Medicine
  • International journal of chronic obstructive…
  • 1 March 2008
Although the prevalence of pulmonary hypertension (PH) in individuals with chronic obstructive pulmonary disease (COPD) is not known precisely, approximately 10%–30% of patients with moderate toExpand
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Keratinocyte growth factor and hepatocyte growth factor/scatter factor are heparin-binding growth factors for alveolar type II cells in fibroblast-conditioned medium.
Epithelial-mesenchymal interactions mediate aspects of normal lung growth and development and are important in the restoration of normal alveolar architecture after lung injury. To determine ifExpand
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Intratracheal instillation of keratinocyte growth factor decreases hyperoxia-induced mortality in rats.
Alveolar type II cell proliferation occurs after many forms of lung injury and is thought to play a critical role in alveolar epithelial repair. Keratinocyte growth factor/fibroblast growth factor 7Expand
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Hepatocyte growth factor. A cytokine mediating endothelial migration in inflammatory arthritis.
OBJECTIVE Angiogenesis is an integral component of the vasculoproliferative phase of rheumatoid arthritis (RA). Recently, a heparin-binding cytokine termed hepatocyte growth factor (HGF), or scatterExpand
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A Randomized Trial of Long-Term Oxygen for COPD with Moderate Desaturation.
BACKGROUND Long-term treatment with supplemental oxygen has unknown efficacy in patients with stable chronic obstructive pulmonary disease (COPD) and resting or exercise-induced moderateExpand
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Keratinocyte growth factor induces angiogenesis and protects endothelial barrier function.
Keratinocyte growth factor (KGF), also called fibroblast growth factor-7, is widely known as a paracrine growth and differentiation factor that is produced by mesenchymal cells and has been thoughtExpand
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Mediators, cytokines, and growth factors in liver-lung interactions.
Multiple mediators have been implicated in the interactions between the liver and the lungs in various disease states. The best characterized mediator of liver-lung interaction is alphaExpand
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