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Lung deposition and efficacy of inhaled formoterol in patients with moderate to severe COPD.
- E. Derom, K. Stråndgarden, V. Schelfhout, L. Borgström, R. Pauwels
- Respiratory medicine
- 1 September 2007
BACKGROUND Little is known about the impact of COPD on lung deposition of inhaled drugs and the relationship between lung-dose and response of pulmonary function measurements. METHODS Nineteen… Expand
Exposure of infants to budesonide through breast milk of asthmatic mothers.
- A. Fält, T. Bengtsson, +4 authors K. Stråndgarden
- The Journal of allergy and clinical immunology
- 1 October 2007
BACKGROUND Maintenance treatment with inhaled corticosteroids is often required for asthmatic nursing women. Data on the transfer of inhaled corticosteroids from plasma to breast milk and the… Expand
Transient paradoxical bronchospasm associated with inhalation of the LAMA AZD9164: analysis of two Phase I, randomised, double-blind, placebo-controlled studies
BackgroundAZD9164 has demonstrated potential as an inhaled, long-acting, muscarinic antagonist (LAMA) bronchodilator. However, in patients with COPD, but not in healthy subjects, a transient initial… Expand
Anti-angiogenic treatment with linomide as adjuvant to surgical castration in experimental prostate cancer.
- B. Hartley‐åsp, J. Vukanović, I. B. Joseph, K. Stråndgarden, J. Poláček, J. Isaacs
- The Journal of urology
- 1 September 1997
PURPOSE Escape from "castration inhibition," be it surgical or chemically induced, is still the major problem in prostate cancer treatment. New agents that can be given as adjuvant therapy are… Expand
Pharmacokinetic Evaluation of Once-Weekly and Once-Monthly Buprenorphine Subcutaneous Injection Depots (CAM2038) Versus Intravenous and Sublingual Buprenorphine in Healthy Volunteers Under Naltrexone…
- M. Albayaty, M. Linden, H. Olsson, M. Johnsson, K. Stråndgarden, F. Tiberg
- Advances in Therapy
- 9 January 2017
AbstractIntroductionCAM2038 q1w (once weekly) and q4w (once monthly) are investigational buprenorphine subcutaneous (SC) formulations based on FluidCrystal® injection depot technology. These two drug… Expand
Absorption and disposition including enterohepatic circulation of (14C) roquinimex after oral administration to healthy volunteers
- K. Stråndgarden, P. Höglund, L. Grönquist, L. Svensson, Per Olov Gunnarsson
- Chemistry, Medicine
- Biopharmaceutics & drug disposition
- 1 March 2000
The absorption and disposition of roquinimex (Linomide®) were studied in four male and two female healthy volunteers. The subjects received a single oral aqueous solution of 14C‐labelled roquinimex,… Expand
The first clinical pilot study of roquinimex (Linomide) in cancer patients with special focus on immunological effects.
- J. Bergh, T. Tötterman, B. Termander, K. Stråndgarden, P. Gunnarsson, B. Nilsson
- Cancer investigation
Roquinimex (Linomide) has been demonstrated to suppress tumor growth in animal models. The effect is at least in part related to enhanced numbers and activity of natural killer (NK) cells. In this… Expand
Clinical pilot study of roquinimex (Linomide®) in patients with autoimmune disease
Dissolution rate‐limited absorption and complete bioavailability of roquinimex in man
- K. Stråndgarden, P. Höglund, Ö. Nordle, J. Poláček, H. Waennman, Per‐Olov Gunnarsson
- Biopharmaceutics & drug disposition
- 1 October 1999
In order to investigate the bioavailability and the rate‐limiting step of the absorption of roquinimex, an oral solution and a tablet formulation (Linomide®) were given to healthy volunteers. The… Expand
Blood MMP-Activity In COPD Patients, Smokers And Healthy Subjects Using A Novel MMP Activity Assay