Long acting muscarinic antagonists for the treatment of chronic obstructive pulmonary disease: a review of current and developing drugs

@article{Mastrodicasa2017LongAM,
  title={Long acting muscarinic antagonists for the treatment of chronic obstructive pulmonary disease: a review of current and developing drugs},
  author={Mark A Mastrodicasa and Christopher A. Droege and Aaron M Mulhall and Neil E Ernst and R. Panos and M. A. Zafar},
  journal={Expert Opinion on Investigational Drugs},
  year={2017},
  volume={26},
  pages={161 - 174}
}
  • Mark A Mastrodicasa, Christopher A. Droege, +3 authors M. A. Zafar
  • Published 2017
  • Medicine
  • Expert Opinion on Investigational Drugs
  • ABSTRACT Introduction: Long acting muscarinic receptor antagonists (LAMA) reverse airflow obstruction by antagonizing para-sympathetic bronchoconstricting effects within the airways. For years, tiotropium, has been the cornerstone LAMA for chronic obstructive pulmonary disease (COPD) management. Recently, new agents, aclidinium bromide, glycopyrronium bromide, and umeclidinium bromide, have been developed and introduced into clinical practice. Areas covered: This article reviews the clinical… CONTINUE READING
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