quazepam

Known as: Quazepamum, 2H-1,4-Benzodiazepine-2-thione, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-, quazepam [Chemical/Ingredient] 
A synthetic benzodiazepine derivative with anxiolytic, sedative and hypnotic properties. Quazepam and its major metabolite 2-oxoquazepam potentiate… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2016
0246819792016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Grapefruit juice (GFJ) inhibits cytochrome P450 (CYP) 3A4 in the gut wall and increases blood concentrations of CYP3A4 substrates… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2004
2004
AIM St John's Wort (SJW) enhances CYP3A4 activity and decreases blood concentrations of CYP3A4 substrates. In this study, the… (More)
Is this relevant?
2004
2004
The study was carried out to identify and characterize kinetically the cytochrome P450 (CYP) enzymes responsible for the major… (More)
Is this relevant?
1987
1987
7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4- benzodiazepine-2-thione (quazepam, Sch 16134, Dormalin… (More)
Is this relevant?
1986
1986
Two benzodiazepine hypnotics, one with an intermediate elimination t1/2 (temazepam, 15 mg) and the other with a long t1/2… (More)
Is this relevant?
1984
1984
Quazepam, a benzodiazepine hypnotic, was studied in normal subjects to evaluate steady-state kinetics of quazepam and of its… (More)
Is this relevant?
1984
1984
The effect of sleep on quazepam kinetics was studied in 12 normal adult men. In a randomized two-way crossover design, each… (More)
Is this relevant?
1983
1983
The safety and hypnotic efficacy of quazepam 30 mg vs placebo in 57 insomniac outpatients were assessed in a randomized… (More)
Is this relevant?
1982
1982
Two investigation benzodiazepine hypnotics with long half-lifes, (30 and 15 mg quazepam and 30 mg flurazepam) were evaluated in… (More)
Is this relevant?
1981
1981
Quazepam, an investigational benzodiazepine, was evaluated in doses of 7.5, 15, and 30 mg in a 12-night protocol including four… (More)
Is this relevant?