Quazepam and flurazepam: Long‐term use and extended withdrawal

@article{Kales1982QuazepamAF,
  title={Quazepam and flurazepam: Long‐term use and extended withdrawal},
  author={Anthony Kales and Edward O. Bixler and Constantin R. Soldatos and Antonlo Vela‐Bueno and Judith A. Jacoby and Joyce D. Kales},
  journal={Clinical Pharmacology \& Therapeutics},
  year={1982},
  volume={32}
}
Two investigational benzodiazepine hypnotics with long half‐lifes, (30 and 15 mg quazepam and 30 mg flurazepam) were evaluated in 47‐night sleep laboratory studies. The effectiveness and side effects of these benzodiazepines were assessed during short‐, intermediate‐, and long‐term use. Subjects were also assessed for presence of rebound insomnia during the 15 days following abrupt withdrawal. Quazepam, 15 and 30 mg, and flurazepam, 30 mg, each were effective in sleep induction and maintenance… 
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TLDR
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