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Prevalence of sleep-disordered breathing in women: effects of gender.
TLDR
The data combined indicate that menopause is a significant risk factor for sleep apnea in women and that hormone replacement appears to be associated with reduced risk. Expand
Effects of age on sleep apnea in men: I. Prevalence and severity.
TLDR
The study shows that the prevalence of sleep apnea tends to increase with age but that the clinical significance (severity) of apnea decreases, and that the sleep laboratory criteria used for diagnosis ofSleep apnea should be adjusted for age. Expand
Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines.
TLDR
It is concluded that in young men and women, modest sleep loss is associated with significant sleepiness, impairment of psychomotor performance, and increased secretion of proinflammatory cytokines. Expand
Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesity.
TLDR
It is suggested that TNF alpha and IL-6 might play a significant role in mediating sleepiness and fatigue in disorders of EDS in humans. Expand
Sleep apnea and daytime sleepiness and fatigue: relation to visceral obesity, insulin resistance, and hypercytokinemia.
TLDR
There is a strong independent association among sleep apnea, visceral obesity, insulin resistance and hypercytokinemia, which may contribute to the pathological manifestations and somatic sequelae of this condition. Expand
Prevalence of sleep disorders in the Los Angeles metropolitan area.
TLDR
Insomnia, nightmares, and hypersomnia were correlated with more frequent general physical and mental health problems and were often chronic and usually started early in life. Expand
Chronic insomnia is associated with nyctohemeral activation of the hypothalamic-pituitary-adrenal axis: clinical implications.
TLDR
It is concluded that insomnia is associated with an overall increase of ACTH and cortisol secretion, which, however, retains a normal circadian pattern, consistent with a disorder of central nervous system hyperarousal rather than one of sleep loss, which is usually associated with no change or decrease in cortisol secretion or a circadian disturbance. Expand
Excessive daytime sleepiness in a general population sample: the role of sleep apnea, age, obesity, diabetes, and depression.
TLDR
It appears that the presence of EDS is more strongly associated with depression and metabolic factors than with sleep-disordered breathing or sleep disruption per se, and patients with a complaint of E DS should be thoroughly assessed for depression and obesity/diabetes independent of whether sleep- disordered breathing is present. Expand
Circadian interleukin-6 secretion and quantity and depth of sleep.
TLDR
It is suggested that a good night's sleep isassociated with decreased daytime secretion of IL-6 and a good sense of well-being and that good sleep is associated with decreased exposure of tissues to the proinflammatory and potentially detrimental actions of IL -6. Expand
Polycystic ovary syndrome is associated with obstructive sleep apnea and daytime sleepiness: role of insulin resistance.
TLDR
The data indicate that SDB and EDS are markedly and significantly more frequent in PCOS women than in premenopausal controls and support the proposal that, independently of gender, sleep apnea might be a manifestation of an endocrine/metabolic abnormality in which insulin resistance plays a principal role. Expand
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