Short-Term Study of Quazepam 15 Milligrams in the Treatment of Insomnia

@article{Lara1983ShortTermSO,
  title={Short-Term Study of Quazepam 15 Milligrams in the Treatment of Insomnia},
  author={Raul Hernandez Lara and Pedro Leal del Rosal and Julia Cristina Ponce},
  journal={Journal of International Medical Research},
  year={1983},
  volume={11},
  pages={162 - 166}
}
The hypnotic efficacy and safety of quazepam 15 mg was compared with placebo in thirty-six out-patients with insomnia. The study was double-blind, with two comparable groups of patients established by random allocation. Following a placebo baseline period, patients took placebo or quazepam for 5 consecutive nights and completed sleep questionnaires the next day. Quazepam was rated better than placebo in terms of sleep quality, sleep induction time, total sleep time, and early morning awakenings… 
View on SAGE
ncbi.nlm.nih.gov
15 Citations

Figures and Tables from this paper

15 Citations

Citation Type

Citation Type

Quazepam: Hypnotic Efficacy and Side Effects
  • A. Kales
  • Medicine, Psychology
    Pharmacotherapy
  • 1990
TLDR
Quazepam is a benzodiazepine hypnotic that can be useful in the adjunctive pharmacologic treatment of insomnia and is more effective with short‐term use, and with continued use it maintains its efficacy in contrast to both of these drugs which show rapid development of tolerance.
Benzodiazepines and zolpidem for chronic insomnia: a meta-analysis of treatment efficacy.
TLDR
Benzodiazepines and zolpidem produced reliable improvements in commonly measured parameters of sleep in patients with chronic insomnia, and presented challenges for developing evidence-based guidelines for the use of hypnotics in the management of chronic insomnia.
Current patterns and future directions in the treatment of insomnia.
  • J. Winkelman, R. Pies
  • Medicine, Psychology
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists
  • 2005
TLDR
There is evidence that improved sleep may improve outcome in some medical and psychiatric illnesses and that at least one agent may be safe and effective in longer-term use.
Nature, Evaluation, and Treatment of Insomnia
TLDR
No single treatment is effective for all forms of insomnia or acceptable to all patients, and additional research is needed to examine optimal treatment algorithms using sequential or combination therapies.
Manifestations and management of chronic insomnia in adults.
TLDR
The Sleep in America Poll, conducted by the National Sleep Foundation, revealed that almost 50 percent of people surveyed had complaints of frequent insomnia, but only 6 percent were formally diagnosed.
Diagnosis and treatment of chronic insomnia: a review.
  • R. Benca
  • Medicine, Psychology
    Psychiatric services
  • 2005
TLDR
Current treatment options do not address the needs of difficult-to-treat patients with chronic insomnia, such as the elderly, and those with comorbid medical and psychiatric conditions.
Sleep maintenance insomnia: strengths and weaknesses of current pharmacologic therapies.
  • R. Rosenberg
  • Psychology, Medicine
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists
  • 2006
TLDR
New agents that offer relief of sleep maintenance insomnia without residual next day impairment while improving next day function are needed.
Nature and Treatment of Insomnia
TLDR
This chapter reviews the nature and treatment of insomnia and describes of validated assessment methods for sleep/wake complaints and current therapeutic options for the management of insomnia, with a predominant emphasis on cognitive-behavioral approaches.
Insomnia nature, diagnosis, and treatment.
Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline.
TLDR
This guideline is designed to establish clinical practice recommendations for the pharmacologic treatment of chronic insomnia in adults, when such treatment is clinically indicated, and includes drugs that are FDA-approved for the treatment of insomnia, as well as several drugs commonly used to treat insomnia without an FDA indication.
...
...