Receptors, Antigen

Known as: Antigen Receptor, Antigen Receptors, Receptor, Antigen 
A cell-surface receptor found on T-cells or B-cells that recognize specific antigenic peptides. Each cell naturally produces a unique receptor that… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2018
020040019572017

Papers overview

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Review
2016
Review
2016
Recent years, we have witnessed significant progresses in both basic and clinical studies regarding novel therapeutic strategies… (More)
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Review
2016
Review
2016
Immunotherapy strategies against cancer are emerging as powerful weapons for treatment of this disease. The success of checkpoint… (More)
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Relapsed acute lymphoblastic leukemia (ALL) is difficult to treat despite the availability of aggressive therapies… (More)
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Highly Cited
2013
Highly Cited
2013
Chimeric antigen receptor-modified T cells with specificity for CD19 have shown promise in the treatment of chronic lymphocytic… (More)
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Highly Cited
2011
Highly Cited
2011
We designed a lentiviral vector expressing a chimeric antigen receptor with specificity for the B-cell antigen CD19, coupled with… (More)
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Highly Cited
2011
Highly Cited
2011
Tumor immunotherapy with T lymphocytes, which can recognize and destroy malignant cells, has been limited by the ability to… (More)
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Highly Cited
2010
Highly Cited
2010
In an attempt to treat cancer patients with ERBB2 overexpressing tumors, we developed a chimeric antigen receptor (CAR) based on… (More)
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Highly Cited
2002
Highly Cited
2002
Class IA phosphoinositide 3-kinases (PI3Ks) are a family of p85/p110 heterodimeric lipid kinases that generate second messenger… (More)
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Highly Cited
2001
Highly Cited
2001
Toll-like receptors have a crucial role in the detection of microbial infection in mammals and insects. In mammals, these… (More)
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Highly Cited
1998
Highly Cited
1998
To better understand the stage(s) of differentiation reached by B-type chronic lymphocytic leukemia (B-CLL) cells and to gain… (More)
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