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Ligand Binding

Ligand Binding is the tight and specific (high affinity) interaction between a small molecule (typically) and a macromolecule (usually protein) that… 
National Institutes of Health

Related topics

Related topics

50 relations
ABCG2 wt AlleleADORA2B protein, humanAMIGO2 protein, humanBRS3 gene

Papers overview

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Highly Cited
2006
Highly Cited
2006
Multivalency in Ligand Design
We define rnultivakncy to be the operation of multiple molecular recognition events of the same kind occurring simultaneously… 
Highly Cited
2006
Highly Cited
2006
Tissue preferential expression of estrogen receptor gene in the marine snail, Thais clavigera.
Highly Cited
2003
Highly Cited
2003
Virus-ligand interactions: identification and characterization of ligand binding by NMR spectroscopy.
We demonstrate the detection and characterization of ligand binding to viruses via NMR. To illustrate the methodology, the… 
Highly Cited
2001
Highly Cited
2001
Noninvasive, quantitative imaging in living animals of a mutant dopamine D2 receptor reporter gene in which ligand binding is uncoupled from signal transduction
The dopamine D2 receptor (D2R) has been used in adenoviral delivery systems and in tumor cell xenografts as an in vivo reporter… 
Review
1999
Review
1999
Integrins: alternative splicing as a mechanism to regulate ligand binding and integrin signaling events
Integrins are a family of transmembrane proteins composed of heterodimers of α and β subunits. With their extracellular domain… 
Highly Cited
1996
Highly Cited
1996
Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion.
Highly Cited
1996
Highly Cited
1996
Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs
Human histocompatibility leukocyte antigen (HLA)-DM is a facilitator of antigen presentation via major histocompatibility complex… 
Highly Cited
1995
Highly Cited
1995
Mosquito ecdysteroid receptor: analysis of the cDNA and expression during vitellogenesis.
Highly Cited
1994
Highly Cited
1994
Rapid endocytosis of interleukin 2 receptors when clathrin‐coated pit endocytosis is inhibited
Highly Cited
1994
Highly Cited
1994
Mutation of an aspartate residue highly conserved among G-protein-coupled receptors results in nonreciprocal disruption of alpha 2-adrenergic receptor-G-protein interactions. A negative charge at…
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