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Ligand Binding

Ligand Binding is the tight and specific (high affinity) interaction between a small molecule (typically) and a macromolecule (usually protein) that… 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Receptor-ligand H-bond pairings have evolved to promote high-affinity binding by reducing competitive interference with water… 
Highly Cited
2003
Highly Cited
2003
We used luminescent CdSe-ZnS core-shell quantum dots (QDs) as energy donors in fluorescent resonance energy transfer (FRET… 
Highly Cited
1998
Highly Cited
1998
The 2.8-A crystal structure of the complex formed by estradiol and the human estrogen receptor-alpha ligand binding domain… 
Highly Cited
1998
Highly Cited
1998
We recently reported the positional cloning of a candidate gene for hereditary hemochromatosis called HFE. The gene product, a… 
Review
1997
Review
1997
The establishment of a vascular supply is required for organ development and differentiation as well as for tissue repair and… 
Highly Cited
1997
Highly Cited
1997
Migration of cells in higher organisms is mediated by adhesion receptors, such as integrins, that link the cell to extracellular… 
Review
1990
Review
1990
UNLABELLED 1. INTRODUCTION Serum albumin possesses a unique capability to bind, covalently or reversibly, a great number of… 
Highly Cited
1988
Highly Cited
1988
A study of the binding of the antibacterial agent trimethoprim to Escherichia coli dihydrofolate reductase was carried out using…