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Ligand Binding

Ligand Binding is the tight and specific (high affinity) interaction between a small molecule (typically) and a macromolecule (usually protein) that… 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
The hydrophobic effect is viewed as the driving force for the aggregation of nonpolar substances with extended lipophilic… 
Highly Cited
2011
Highly Cited
2011
Ligand binding involves breakage of hydrogen bonds with water molecules and formation of new hydrogen bonds between protein and… 
Highly Cited
2006
Highly Cited
2006
We define rnultivakncy to be the operation of multiple molecular recognition events of the same kind occurring simultaneously… 
Highly Cited
2003
Highly Cited
2003
We demonstrate the detection and characterization of ligand binding to viruses via NMR. To illustrate the methodology, the… 
Highly Cited
2000
Highly Cited
2000
To elucidate the molecular basis for the interaction of ligands with the human melanocortin-4 receptor (hMC4R), agonist structure… 
Highly Cited
1997
Highly Cited
1997
Previous studies have shown that integrin α chain tails make strong positive contributions to integrin-mediated cell adhesion. We… 
Highly Cited
1990
Highly Cited
1990
The ligand-binding function of integrin adhesion receptors depends on divalent cations. A mutant alpha IIb beta 3 integrin… 
Highly Cited
1990
Highly Cited
1990
Evidence is presented for a role of disulfide bridging in forming the ligand binding site of the beta 2-adrenergic receptor (beta…