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ABCG2 wt Allele

Known as: EST157481, CDw338, ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (Junior Blood Group) wt Allele 
Human ABCG2 wild-type allele is located within 4q22 and is approximately 67 kb in length. This allele, which encodes ATP-binding cassette sub-family… 
National Institutes of Health

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9 relations
4q22ABCG2 geneABCG2 protein, humanDrug Efflux

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Stable knock-down of efflux transporters leads to reduced glucuronidation in UGT1A1-overexpressing HeLa cells: the evidence for glucuronidation-transport interplay.
Efflux of glucuronide is facilitated by the membrane transporters including BCRP and MRPs. In this study, we aimed to determine… 
2007
2007
Involvement of Breast Cancer Resistance Protein (BCRP/ABCG2) in the Biliary Excretion and Intestinal Efflux of Troglitazone Sulfate, the Major Metabolite of Troglitazone with a Cholestatic Effect
Troglitazone sulfate (TGZS) is the major metabolite of troglitazone (TGZ), an antidiabetic agent, and thought to be a cause of… 
Highly Cited
2006
Highly Cited
2006
The Important Role of Bcrp (Abcg2) in the Biliary Excretion of Sulfate and Glucuronide Metabolites of Acetaminophen, 4-Methylumbelliferone, and Harmol in Mice
The role of Mrp2, Bcrp, and P-glycoprotein in the biliary excretion of acetaminophen sulfate (AS) and glucuronide (AG), 4… 
2006
2006
BCRP/ABCG2 levels account for the resistance to topoisomerase I inhibitors and reversal effects by gefitinib in non-small cell lung cancer
Purpose: Breast cancer resistance protein (BCRP) confers resistance against topoisomerase I inhibitors in cancer cells. Very… 
Review
2006
Review
2006
Multidrug resistance proteins and folate supplementation: therapeutic implications for antifolates and other classes of drugs in cancer treatment
Over the past decades, numerous reports have covered the crucial role of multidrug resistance (MDR) transporters in the efficacy… 
Highly Cited
2005
Highly Cited
2005
Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2
The ATP binding cassette (ABC) half-transporter ABCG2 (MXR/BCRP/ABCP) is associated with mitoxantrone resistance accompanied by… 
Highly Cited
2005
Highly Cited
2005
EFFECTS OF DIHYDROPYRIDINES AND PYRIDINES ON MULTIDRUG RESISTANCE MEDIATED BY BREAST CANCER RESISTANCE PROTEIN: IN VITRO AND IN VIVO STUDIES
Breast cancer resistance protein (BCRP, ABCG2) is a recently identified member of the ATP-binding cassette family of cell surface… 
2005
2005
Characterization of Polarized Expression of Point- or Deletion-Mutated Human BCRP/ABCG2 in LLC-PK1 Cells
No HeadingPurpose.In polarized cells, such as hepatocytes and intestinal epithelial cells, transporters are localized on the… 
1995
1995
Prognostic factors for head and neck tumor recurrence.
The introduction of new treatment methods has stimulated the identification of further prognostic factors capable of defining the… 
1994
1994
Drinking pattern and blood pressure.
Large amounts of alcohol are known to increase blood pressure. There is little evidence about the effect of binge drinking of… 
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