ABCG2 protein, human

Known as: methotrexate carrier protein, human, methotrexate transporter protein, human, CDw338 
ATP-binding cassette sub-family G member 2 (655 aa, ~72 kDa) is encoded by the human ABCG2 gene. This protein is involved in the transport of urate… (More)
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Since cloning of the ATP-binding cassette (ABC) family member breast cancer resistance protein (BCRP/ABCG2) and its… (More)
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Review
2009
Review
2009
ABCG2, or breast cancer resistance protein (BCRP), is an ABC transporter that has been the subject of intense study since its… (More)
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Highly Cited
2009
Highly Cited
2009
Breast cancer resistance protein (BCRP/ABCG2) is a molecular determinant of pharmacokinetic properties of many drugs in humans… (More)
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Review
2009
Review
2009
The multidrug transporter ABCG2 (BCRP/MXR/ABCP) can actively extrude a broad range of endogenous and exogenous substrates across… (More)
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Highly Cited
2008
Highly Cited
2008
The Breast Cancer Resistance Protein (BCRP/ABCG2) is a transporter restricting absorption and enhancing excretion of many… (More)
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Highly Cited
2004
Highly Cited
2004
Imatinib mesylate (STI571), a potent tyrosine kinase inhibitor, is successfully used in the treatment of chronic myelogenous… (More)
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Review
2003
Review
2003
Observations of functional adenosine triphosphate (ATP)-dependent drug efflux in certain multidrug-resistant cancer cell lines… (More)
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Highly Cited
2001
Highly Cited
2001
We sought to characterize the interactions of flavopiridol with members of the ATP-binding cassette (ABC) transporter family… (More)
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Highly Cited
2001
Highly Cited
2001
The fluorescent compounds rhodamine 123, LysoTracker Green DMD-26, mitoxantrone, and BODIPY-prazosin were used with the… (More)
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Highly Cited
1998
Highly Cited
1998
MCF-7/AdrVp is a multidrug-resistant human breast cancer subline that displays an ATP-dependent reduction in the intracellular… (More)
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