Skip to search formSkip to main contentSkip to account menu

ABCG2 protein, human

Known as: methotrexate carrier protein, human, methotrexate transporter protein, human, CDw338 
ATP-binding cassette sub-family G member 2 (655 aa, ~72 kDa) is encoded by the human ABCG2 gene. This protein is involved in the transport of urate… 
National Institutes of Health

Related topics

Related topics

19 relations
ABCG2 geneABCG2 wt AlleleAdenosine TriphosphatasesCellular Membrane

Broader (2)

ATP Binding Cassette Transporter, Sub-Family G, Member 2Neoplasm Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Efflux transporter breast cancer resistance protein dominantly expresses on the membrane of red blood cells, hinders partitioning of its substrates into the cells, and alters drug–drug interaction…
  • Pu ShiM. Liao C. Xia
  • Xenobiotica; the fate of foreign compounds in…
  • 2018
  • Corpus ID: 21458213
Abstract 1. Red blood cell (RBC) partitioning is important in determining pharmacokinetic and pharmacodynamic properties of a… 
2018
2018
2018 Title : Ligand-based and Structure-based Studies to Understand the Molecular Basis of Inhibition of ABC Transporters Expressed in the Liver Abstract in English
in English ABC-transporters such as the bile salt export pump (BSEP), the breast cancer resistance protein (BCRP) and P… 
2012
2012
PHARMACOGENOINFORMATICS: MODELING OF P-GLYCOPROTEIN AND NOVEL APPROACH OF In Silico DRUG DESIGNING BASED ON GENETIC VARIATION OF MDR1 GENE INVOLVED IN STATIN RESISTANCE
Statins are the most prescribed drugs, highly effective in reducing the risk of cardiovascular and cerebrovascular events… 
Review
2011
Review
2011
The industrial exporter-distributor trade relationship - A portrayal of the development path derived from diverging agendas
Marketing activities through the use of distributors is a common means for exporters to reach markets. However, research is… 
2011
2011
Expression of CD44,CD133,and ABCG2 as Potential Cancer Biomarker Proteins
Cancer biomarkers can provide the chance to develop therapies for cancer during its the natural progression,to either inhibit or… 
2009
2009
Breast cancer resistance protein 1 (bcrp) and p-glycoprotein (mdr1) are key players in renal regeneration after ischemic injury
2007
2007
The ATP-binding cassette transporter ABCG2 (BCRP) and ABCB1 (MDR1) variants are not associated with disease susceptibility and disease phenotype in Hungarian patients with inflammatory bowel diseases
2007
2007
The Role of Multi-Drug Resistance Associated Protein 4 and P-glycoprotein in Resistance of Neuroblastoma to Topotecan and Irinotecan
High-risk neuroblastoma presents a significant therapeutic challenge because the 5-year survival rate remains less than 30… 
2006
2006
by a Tyrosine Kinase Inhibitor Topotecan Central Nervous System Penetration Is Altered
A potential strategy to increase the efficacy of topotecan to treat central nervous system (CNS) malignancies is modulation of… 
Review
2003
Review
2003
Functional Characterization of Human Breast Cancer Resistance Protein ( BCRP , ABCG 2 ) Expressed in the Oocytes of Xenopus laevis
To evaluate the function and substrate specificity of human breast cancer resistance protein (BCRP, ABCG2) in the absence of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)