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Drug Efflux

Transport of drugs out of a cell. A mechanism of drug resistance.
National Institutes of Health

Related topics

Related topics

41 relations
ABCA1 protein, humanABCB1 2 AlleleABCB1 geneABCB1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Doxorubicin loaded iron oxide nanoparticles overcome multidrug resistance in cancer in vitro.
Highly Cited
2007
Highly Cited
2007
CD33 expression and P-glycoprotein-mediated drug efflux inversely correlate and predict clinical outcome in patients with acute myeloid leukemia treated with gemtuzumab ozogamicin monotherapy.
Gemtuzumab ozogamicin (GO) contains an anti-CD33 antibody to facilitate uptake of a toxic calicheamicin-gamma(1) derivative… 
Review
2006
Review
2006
Mechanisms and strategies to overcome multiple drug resistance in cancer
Highly Cited
2004
Highly Cited
2004
The use of a dendrimer-propranolol prodrug to bypass efflux transporters and enhance oral bioavailability.
Highly Cited
2004
Highly Cited
2004
Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder.
Highly Cited
2002
Highly Cited
2002
Endogenous drug transporters in in vitro and in vivo models for the prediction of drug disposition in man.
Review
1998
Review
1998
Evolutionary origins of multidrug and drug-specific efflux pumps in bacteria.
The available genomic sequences of three pathogenic and three nonpathogenic bacteria were analyzed to identify known and putative… 
Review
1996
Review
1996
Experimental reversal of P-glycoprotein-mediated multidrug resistance by pharmacological chemosensitisers.
Review
1994
Review
1994
Multidrug resistance pumps in bacteria: variations on a theme.
Highly Cited
1991
Highly Cited
1991
Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug resistant cells.
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