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ABCB1 gene

Known as: ABC20, gene mdr1, GP170 
This gene plays a role in multi-drug resistance and is involved in blood-brain barrier transport.
National Institutes of Health

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12 relations
ABCB1 protein, humanCrohn DiseaseDrug EffluxGallbladder Carcinoma

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ABCB1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Association between two polymorphisms of ABCB1 and breast cancer risk in the current studies: a meta-analysis
Previous epidemiological studies have evaluated the association between the ABCB1 polymorphism and the risk of breast cancer with… 
2009
2009
Visions for Required Postgraduate Year 1 Residency Training by 2020: A Comparison of Actual versus Projected Expansion
Study Objective. To explore the feasibility of expanding postgraduate year (PGY) 1 residency training as proposed by the American… 
2007
2007
[Chemoresistance of CD133(+) tumor stem cells from human brain glioma].
OBJECTIVE To explore the multidrug resistance (MDR) mechanism of ABC superfamily transporters in the tumor stem cells(TSC) from… 
2006
2006
ABCB1 2677G>T/A Genotype and Paclitaxel Pharmacogenetics in Ovarian Cancer
To the Editor: Green et al. ([1][1]) identified ABCB1 2677G>T/A genotype as a marker of response to paclitaxel therapy in ovarian… 
2003
2003
Repetitive doxorubicin treatment of glioblastoma enhances the PGP expression--a special role for endothelial cells.
The glioblastoma is the highest dedifferentiated form of astrocytic brain tumors, which is refractory to chemotherapy in most… 
2002
2002
Identification and characterization of the canine multidrug resistance-associated protein.
Human multidrug resistance protein 1 (MRP1) confers resistance to the Vinca alkaloids, the anthracyclines, and the… 
1999
1999
Co-operative binding sites for transported substrates in the multiple drug resistance transporter Mdr1.
Suramin, a known inhibitor of ATP binding enzymes with six negatively charged sulfonic acid groups, stimulated the ATPase… 
1999
1999
Cmdr1, a Chicken P-Glycoprotein, Confers Multidrug Resistance and Interacts with Estradiol
Abstract We have cloned from a chicken intestinal cDNA library Cmdr1, the first avian P-glycoprotein. Cmdr1 is 67% and 69… 
Review
1997
Review
1997
Multidrug resistance in breast cancer--is the jury in yet?
The term ‘‘multidrug resistance’’ has come to mean different things to different people. Initially, it was coined to describe the… 
1991
1991
Effect of recombinant fibroblast interferon and recombinant immune interferon on growth and the antigenic phenotype of multidrug-resistant human glioblastoma multiforme cells.
To study the effect of drug resistance on the response of stage IV astrocytomas to interferon, a human glioblastoma multiforme… 
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