ABCB1 gene

Known as: ABC20, gene mdr1, GP170 
This gene plays a role in multi-drug resistance and is involved in blood-brain barrier transport.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2018
02040608019802018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Recent studies have reported the clinical importance of CYP2C19 and ABCB1 polymorphisms in an individualized approach to… (More)
  • table 1
  • table 2
  • table 3
Is this relevant?
2009
2009
The aim of this study was to determine the significance of three most common single-nucleotide polymorphisms (SNPs) of ABCB1 gene… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • table 3
Is this relevant?
2009
2009
AIMS Efavirenz exhibits pharmacokinetic variability causing varied clinical response. The aim was to develop an integrated… (More)
Is this relevant?
2007
2007
INTRODUCTION The human multidrug resistance gene ATP-binding cassette B1 (ABCB1) codes for P-glycoprotein (P-gp), an important… (More)
Is this relevant?
2007
2007
P-glycoprotein (PGP) is a polymorphic transporter encoded by the ABCB1 gene that contributes to the access of xenobiotics into… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2005
Highly Cited
2005
BACKGROUND A significant number of patients treated with anthracyclines develop cardiotoxicity (anthracycline-induced… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
Is this relevant?
2004
2004
The multidrug transporter P-glycoprotein is suspected of contributing to pharmacoresistance in temporal lobe epilepsy (TLE). To… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
OBJECTIVES There is increasing evidence that polymorphism of the ABCB1 (MDR1) gene contributes to interindividual variability in… (More)
Is this relevant?
2003
2003
OBJECTIVE Mutations in the ABCB1 gene have been associated with decreased expression and net function of P-glycoprotein (P-gp… (More)
Is this relevant?
2002
2002
BACKGROUND Tacrolimus is a substrate of P-glycoprotein (PGP) encoded by the multidrug resistant (MDR)1 gene (ABCB1). PGP, a… (More)
Is this relevant?