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ABCG2 gene

Known as: EST157481, ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (Junior Blood Group), MXR 
This gene plays a role in xenobiotic transport and multi-drug resistance.
National Institutes of Health

Related topics

Related topics

8 relations
ABCG2 protein, humanABCG2 wt AlleleDrug EffluxHomo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Role of breast cancer resistance protein (Bcrp/Abcg2) in fetal protection during gestation in rat.
Highly Cited
2006
Highly Cited
2006
Expression of breast cancer resistance protein (BCRP/ABCG2) in human placenta throughout gestation and at term before and after labor.
Breast cancer resistance protein, BCRP, is a multidrug resistance protein that is highly expressed in the human placenta. In… 
Highly Cited
2006
Highly Cited
2006
EXPRESSION AND FUNCTIONAL ACTIVITY OF BREAST CANCER RESISTANCE PROTEIN (BCRP, ABCG2) TRANSPORTER IN THE HUMAN CHORIOCARCINOMA CELL LINE BEWO
1 Breast cancer resistance protein (BCRP, ABCG2) is a drug efflux transporter that is believed to affect the drug disposition of… 
Highly Cited
2005
Highly Cited
2005
Investigation of Efflux Transport of Dehydroepiandrosterone Sulfate and Mitoxantrone at the Mouse Blood-Brain Barrier: A Minor Role of Breast Cancer Resistance Protein
Breast cancer resistance protein (Bcrp/Abcg2) is a new efflux transporter found at the blood-brain barrier (BBB) of humans and… 
Highly Cited
2005
Highly Cited
2005
Functional expression of ABCG2 transporter in human neural stem/progenitor cells
Highly Cited
2005
Highly Cited
2005
Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2).
The human BCRP (breast cancer resistance protein, also known as ABCG2) is an ABC (ATP-binding cassette) transporter that extrudes… 
Highly Cited
2005
Highly Cited
2005
Expression Profiling of ABC Transporters in a Drug-Resistant Breast Cancer Cell Line Using AmpArray
ATP-binding cassette (ABC) membrane proteins comprise a superfamily of transporters with a wide variety of substrates. Humans… 
Highly Cited
2005
Highly Cited
2005
Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2
The ATP binding cassette (ABC) half-transporter ABCG2 (MXR/BCRP/ABCP) is associated with mitoxantrone resistance accompanied by… 
Highly Cited
2004
Highly Cited
2004
Consequences of bile duct obstruction on intestinal expression and function of multidrug resistance-associated protein 2.
BACKGROUND & AIMS Multidrug resistance-associated protein 2 (MRP2), a transporter of organic anions in hepatocytes, renal… 
Highly Cited
2001
Highly Cited
2001
Inhibition of BCRP-mediated drug efflux by fumitremorgin-type indolyl diketopiperazines.
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