ABCG2 gene

Known as: EST157481, ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (Junior Blood Group), MXR 
This gene plays a role in xenobiotic transport and multi-drug resistance.
National Institutes of Health

Papers overview

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Review
2009
Review
2009
ABCG2, or breast cancer resistance protein (BCRP), is an ABC transporter that has been the subject of intense study since its… (More)
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Highly Cited
2009
Highly Cited
2009
Gout based on hyperuricemia is a common disease with a genetic predisposition, which causes acute arthritis. The ABCG2/BCRP gene… (More)
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Highly Cited
2006
Highly Cited
2006
ABCG2 is a ubiquitous ATP-binding cassette transmembrane protein that is important in clinical drug resistance. Little is known… (More)
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Highly Cited
2005
Highly Cited
2005
Recently, several human cancers including leukemia and breast and brain tumors were found to contain stem-like cancer cells… (More)
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Highly Cited
2005
Highly Cited
2005
Contamination of milk with drugs, pesticides and other xenotoxins can pose a major health risk to breast-fed infants and dairy… (More)
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Highly Cited
2004
Highly Cited
2004
Our studies demonstrate that the ABC transporter and marker of stem and progenitor cells known as the breast cancer resistance… (More)
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Review
2003
Review
2003
Observations of functional adenosine triphosphate (ATP)-dependent drug efflux in certain multidrug-resistant cancer cell lines… (More)
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Highly Cited
2003
Highly Cited
2003
Recent studies have shown that mutations at amino-acid 482 in the ABCG2 gene affect the substrate specificity of the protein. To… (More)
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Highly Cited
2002
Highly Cited
2002
A promising and increasingly exploited property of hematopoietic stem cells is their ability to efflux the fluorescent dye… (More)
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Highly Cited
2002
Highly Cited
2002
The human ATP-binding cassette superfamily G (White) member 2 (ABCG2) gene and its murine homologue breast cancer resistance… (More)
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