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T-Cell Receptor

Known as: T Cell Antigen Receptor, T-Cell Antigen Receptors, Major Histocompatibility Complex Receptor 
Heterodimeric antigen receptors present on the surface of T-cells. Two T-cell antigen receptors have been identified, consisting of heterodimeric 40… 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Co-stimulatory and co-inhibitory receptors have a pivotal role in T cell biology, as they determine the functional outcome of T… 
Highly Cited
2001
Highly Cited
2001
Programmed death 1 (PD-1)–deficient mice develop a variety of autoimmune-like diseases, which suggests that this immunoinhibitory… 
Highly Cited
2000
Highly Cited
2000
This report shows that cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) plays a key role in T cell–mediated dominant… 
Highly Cited
1998
Highly Cited
1998
Peripheral tolerance may be maintained by a population of regulatory/suppressor T cells that prevent the activation of… 
Highly Cited
1996
Highly Cited
1996
The requirements for T cell activation have been reported to vary widely depending on the state of the T cell, the type of… 
Highly Cited
1996
Highly Cited
1996
The central event in the cellular immune response to invading microorganisms is the specific recognition of foreign peptides… 
Highly Cited
1992
Highly Cited
1992
To study the factors that determine whether CD4+ T cells produce interleukin 4 (IL-4) or interferon gamma (IFN-gamma) upon… 
Highly Cited
1989
Highly Cited
1989
THE crucial role of the thymus in immunological tolerance1–5 has been demonstrated by establishing that T cells are positively… 
Review
1988
Review
1988
The four distinct T-cell antigen receptor polypeptides (α, β, γ, δ) form two different heterodimers (α:β and γ:δ) that are very…