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T-Cell Receptor

Known as: T Cell Antigen Receptor, T-Cell Antigen Receptors, Major Histocompatibility Complex Receptor 
Heterodimeric antigen receptors present on the surface of T-cells. Two T-cell antigen receptors have been identified, consisting of heterodimeric 40… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Adaptive immune recognition is mediated by antigen receptors on B and T cells generated by somatic recombination during lineage… Expand
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Review
2018
Review
2018
For many cancer types, the immune system plays an essential role in their development and growth. Based on these rather novel… Expand
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Review
2018
Review
2018
The peculiarity of T cell is their ability to recognize an infinite range of self and foreign antigens. This ability is achieved… Expand
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Review
2018
Review
2018
Viral vectors provide an efficient means for modification of eukaryotic cells, and their use is now commonplace in academic… Expand
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Review
2018
Review
2018
T cell discrimination of self and non-self is predicated on αβ T cell receptor (TCR) co-recognition of peptides presented by MHC… Expand
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Highly Cited
2000
Highly Cited
2000
This report shows that cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) plays a key role in T cell–mediated dominant… Expand
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Highly Cited
1998
Highly Cited
1998
Peripheral tolerance may be maintained by a population of regulatory/suppressor T cells that prevent the activation of… Expand
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Highly Cited
1996
Highly Cited
1996
The requirements for T cell activation have been reported to vary widely depending on the state of the T cell, the type of… Expand
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Highly Cited
1994
Highly Cited
1994
We have used organ culture of fetal thymic lobes from T cell receptor (TCR) transgenic beta 2M(-/-) mice to study the role of… Expand
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Review
1988
Review
1988
The four distinct T-cell antigen receptor polypeptides (α, β, γ, δ) form two different heterodimers (α:β and γ:δ) that are very… Expand
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