Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 205,587,804 papers from all fields of science
Search
Sign In
Create Free Account
T-Cell Receptor
Known as:
T Cell Antigen Receptor
, T-Cell Antigen Receptors
, Major Histocompatibility Complex Receptor
Expand
Heterodimeric antigen receptors present on the surface of T-cells. Two T-cell antigen receptors have been identified, consisting of heterodimeric 40…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
22 relations
Narrower (7)
ALT-801
CD19-specific chimeric antigen receptor
CD8 receptor
IL13-zetakine
Expand
CD3 Antigens
Complementarity Determining Regions
Gene Rearrangement, T-Lymphocyte
Genes, T-Cell Receptor
Expand
Broader (1)
Receptors, Antigen
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Molecular mechanisms of T cell co-stimulation and co-inhibition
Lieping Chen
,
D. Flies
Nature Reviews Immunology
2013
Corpus ID: 3912789
Co-stimulatory and co-inhibitory receptors have a pivotal role in T cell biology, as they determine the functional outcome of T…
Expand
Highly Cited
2001
Highly Cited
2001
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
Y. Latchman
,
C. Wood
,
+18 authors
G. Freeman
Nature Immunology
2001
Corpus ID: 27659586
Programmed death 1 (PD-1)–deficient mice develop a variety of autoimmune-like diseases, which suggests that this immunoinhibitory…
Expand
Highly Cited
2000
Highly Cited
2000
Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4
Takeshi Takahashi
,
Tomoyuki Tagami
,
+5 authors
S. Sakaguchi
The Journal of experimental medicine
2000
Corpus ID: 8768132
This report shows that cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) plays a key role in T cell–mediated dominant…
Expand
Highly Cited
1998
Highly Cited
1998
CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production
A. Thornton
,
E. Shevach
The Journal of experimental medicine
1998
Corpus ID: 3782261
Peripheral tolerance may be maintained by a population of regulatory/suppressor T cells that prevent the activation of…
Expand
Highly Cited
1996
Highly Cited
1996
T Cell Activation Determined by T Cell Receptor Number and Tunable Thresholds
A. Viola
,
A. Lanzavecchia
Science
1996
Corpus ID: 45276598
The requirements for T cell activation have been reported to vary widely depending on the state of the T cell, the type of…
Expand
Highly Cited
1996
Highly Cited
1996
An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex
K. Garcia
,
M. Degano
,
+5 authors
I. Wilson
Science
1996
Corpus ID: 30500565
The central event in the cellular immune response to invading microorganisms is the specific recognition of foreign peptides…
Expand
Highly Cited
1994
Highly Cited
1994
T cell receptor antagonist peptides induce positive selection
K. Hogquist
,
S. Jameson
,
W. Heath
,
J. Howard
,
M. Bevan
,
F. Carbone
Cell
1994
Corpus ID: 31908126
Highly Cited
1992
Highly Cited
1992
The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice
R. Seder
,
W. Paul
,
M. Davis
,
B. Fazekas de St. Groth
The Journal of experimental medicine
1992
Corpus ID: 11132582
To study the factors that determine whether CD4+ T cells produce interleukin 4 (IL-4) or interferon gamma (IFN-gamma) upon…
Expand
Highly Cited
1989
Highly Cited
1989
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
H. Pircher
,
K. Bürki
,
R. Lang
,
H. Hengartner
,
R. Zinkernagel
Nature
1989
Corpus ID: 4263272
THE crucial role of the thymus in immunological tolerance1–5 has been demonstrated by establishing that T cells are positively…
Expand
Review
1988
Review
1988
T-cell antigen receptor genes and T-cell recognition
Mark M. Davis
,
P. Bjorkman
Nature
1988
Corpus ID: 4304261
The four distinct T-cell antigen receptor polypeptides (α, β, γ, δ) form two different heterodimers (α:β and γ:δ) that are very…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
,
Terms of Service
, and
Dataset License
ACCEPT & CONTINUE