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T-Cell Receptor

Known as: T Cell Antigen Receptor, T-Cell Antigen Receptors, Major Histocompatibility Complex Receptor 
Heterodimeric antigen receptors present on the surface of T-cells. Two T-cell antigen receptors have been identified, consisting of heterodimeric 40… 
National Institutes of Health

Related topics

Related topics

22 relations

Narrower (7)

ALT-801CD19-specific chimeric antigen receptorCD8 receptorIL13-zetakine
CD3 AntigensComplementarity Determining RegionsGene Rearrangement, T-LymphocyteGenes, T-Cell Receptor

Broader (1)

Receptors, Antigen

Papers overview

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Highly Cited
2002
Highly Cited
2002
Origin of regulatory T cells with known specificity for antigen
T cell receptor agonists can induce the differentiation of regulatory T (TR) cells. We report here that the immunoglobulin… 
Highly Cited
2002
Highly Cited
2002
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
Tcell antigen receptor (TCR) ligation initiates tyrosine kinase activation, signaling complex assembly, and immune synapse… 
Highly Cited
2002
Highly Cited
2002
Two Subsets of Naive T Helper Cells with Distinct T Cell Receptor Excision Circle Content in Human Adult Peripheral Blood
During ageing thymic function declines and is unable to meet the demand for peripheral T helper (Th) cell replenishment… 
Highly Cited
2001
Highly Cited
2001
Costimulation of CD8αβ T cells by NKG2D via engagement by MIC induced on virus-infected cells
NKG2D is an activating receptor that stimulates innate immune responses by natural killer cells upon engagement by MIC ligands… 
Highly Cited
1998
Highly Cited
1998
LAT The ZAP-70 Tyrosine Kinase Substrate that Links T Cell Receptor to Cellular Activation
Highly Cited
1995
Highly Cited
1995
Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
Using antigen-specific T cell clones and peptide-pulsed antigen- presenting cells (APCs) we investigated the mechanisms that lead… 
Highly Cited
1990
Highly Cited
1990
Homing of a γδ thymocyte subset with homogeneous T-cell receptors to mucosal epithelia
IN mice γδ T-cell populations with distinct T-cell receptor (TCR) repertoires and homing properties have been identified… 
Highly Cited
1989
Highly Cited
1989
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
THE crucial role of the thymus in immunological tolerance1–5 has been demonstrated by establishing that T cells are positively… 
Review
1988
Review
1988
The T cell receptor/CD3 complex: a dynamic protein ensemble.
A large body of information about antigen receptors on the surface of T lymphocytes has been gathered in the last five years (1… 
Highly Cited
1988
Highly Cited
1988
Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells
T-cell receptors and T-cell subsets were analysed in T-cell receptor transgenic mice expressing α and β T-cell receptor genes… 
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