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T-Cell Receptor

Known as: T Cell Antigen Receptor, T-Cell Antigen Receptors, Major Histocompatibility Complex Receptor 
Heterodimeric antigen receptors present on the surface of T-cells. Two T-cell antigen receptors have been identified, consisting of heterodimeric 40… Expand
National Institutes of Health

Related topics

Related topics

22 relations

Narrower (7)

ALT-801CD19-specific chimeric antigen receptorCD8 receptorIL13-zetakine
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CD3 AntigensComplementarity Determining RegionsGene Rearrangement, T-LymphocyteGenes, T-Cell Receptor
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Broader (1)

Receptors, Antigen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Using T Cell Receptor Repertoires to Understand the Principles of Adaptive Immune Recognition.
Adaptive immune recognition is mediated by antigen receptors on B and T cells generated by somatic recombination during lineage… Expand
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Review
2018
Review
2018
Adoptive cellular therapies: the current landscape
For many cancer types, the immune system plays an essential role in their development and growth. Based on these rather novel… Expand
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Review
2018
Review
2018
Single Cell T Cell Receptor Sequencing: Techniques and Future Challenges
The peculiarity of T cell is their ability to recognize an infinite range of self and foreign antigens. This ability is achieved… Expand
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Review
2018
Review
2018
Clinical use of lentiviral vectors
Viral vectors provide an efficient means for modification of eukaryotic cells, and their use is now commonplace in academic… Expand
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Review
2018
Review
2018
Understanding the drivers of MHC restriction of T cell receptors
T cell discrimination of self and non-self is predicated on αβ T cell receptor (TCR) co-recognition of peptides presented by MHC… Expand
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Highly Cited
2000
Highly Cited
2000
Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4
This report shows that cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) plays a key role in T cell–mediated dominant… Expand
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Highly Cited
1998
Highly Cited
1998
CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production
Peripheral tolerance may be maintained by a population of regulatory/suppressor T cells that prevent the activation of… Expand
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Highly Cited
1996
Highly Cited
1996
T Cell Activation Determined by T Cell Receptor Number and Tunable Thresholds
The requirements for T cell activation have been reported to vary widely depending on the state of the T cell, the type of… Expand
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Highly Cited
1994
Highly Cited
1994
T cell receptor antagonist peptides induce positive selection
We have used organ culture of fetal thymic lobes from T cell receptor (TCR) transgenic beta 2M(-/-) mice to study the role of… Expand
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Review
1988
Review
1988
T-cell antigen receptor genes and T-cell recognition
The four distinct T-cell antigen receptor polypeptides (α, β, γ, δ) form two different heterodimers (α:β and γ:δ) that are very… Expand
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