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T-Cell Receptor

Known as: T Cell Antigen Receptor, T-Cell Antigen Receptors, Major Histocompatibility Complex Receptor 
Heterodimeric antigen receptors present on the surface of T-cells. Two T-cell antigen receptors have been identified, consisting of heterodimeric 40… 
National Institutes of Health

Related topics

Related topics

22 relations

Narrower (7)

ALT-801CD19-specific chimeric antigen receptorCD8 receptorIL13-zetakine
CD3 AntigensComplementarity Determining RegionsGene Rearrangement, T-LymphocyteGenes, T-Cell Receptor

Broader (1)

Receptors, Antigen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Molecular mechanisms of T cell co-stimulation and co-inhibition
Co-stimulatory and co-inhibitory receptors have a pivotal role in T cell biology, as they determine the functional outcome of T… 
Highly Cited
2001
Highly Cited
2001
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
Programmed death 1 (PD-1)–deficient mice develop a variety of autoimmune-like diseases, which suggests that this immunoinhibitory… 
Highly Cited
2000
Highly Cited
2000
Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4
This report shows that cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) plays a key role in T cell–mediated dominant… 
Highly Cited
1998
Highly Cited
1998
CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production
Peripheral tolerance may be maintained by a population of regulatory/suppressor T cells that prevent the activation of… 
Highly Cited
1996
Highly Cited
1996
T Cell Activation Determined by T Cell Receptor Number and Tunable Thresholds
The requirements for T cell activation have been reported to vary widely depending on the state of the T cell, the type of… 
Highly Cited
1996
Highly Cited
1996
An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex
The central event in the cellular immune response to invading microorganisms is the specific recognition of foreign peptides… 
Highly Cited
1994
Highly Cited
1994
T cell receptor antagonist peptides induce positive selection
Highly Cited
1992
Highly Cited
1992
The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice
To study the factors that determine whether CD4+ T cells produce interleukin 4 (IL-4) or interferon gamma (IFN-gamma) upon… 
Highly Cited
1989
Highly Cited
1989
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
THE crucial role of the thymus in immunological tolerance1–5 has been demonstrated by establishing that T cells are positively… 
Review
1988
Review
1988
T-cell antigen receptor genes and T-cell recognition
The four distinct T-cell antigen receptor polypeptides (α, β, γ, δ) form two different heterodimers (α:β and γ:δ) that are very… 
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