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Complementarity Determining Regions

Known as: Hypervariable Region, Immunoglobulin, Regions, Complementarity-Determining, Immunoglobulin Hypervariable Regions 
Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from… 
National Institutes of Health

Related topics

Related topics

12 relations

Narrower (3)

Complementarity Determining Region 1Complementarity Determining Region 2Complementarity Determining Region 3
Immunoglobulin Heavy ChainsImmunoglobulin Light ChainsImmunoglobulin Variable RegionImmunoglobulin kappa-Chains

Papers overview

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Highly Cited
1999
Highly Cited
1999
Analysis of the Critical Domain in the V3 Loop of Human Immunodeficiency Virus Type 1 gp120 Involved in CCR5 Utilization
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) infection of CD4+ lymphocytes and macrophages involves interaction of the… 
Highly Cited
1998
Highly Cited
1998
Independent induction of senescence by p16INK4a and p21CIP1 in spontaneously immortalized human fibroblasts.
In this work, we address the question of whether replicative senescence can be induced in immortal nontumorigenic human… 
Highly Cited
1998
Highly Cited
1998
Collection, tumor contamination, and engraftment kinetics of highly purified hematopoietic progenitor cells to support high dose therapy in multiple myeloma.
Unfractionated peripheral blood stem cell (PBSC) grafts contain measurable quantities of myeloma cells and are therefore a… 
Highly Cited
1995
Highly Cited
1995
Crystal structure of the beta chain of a T cell antigen receptor.
The crystal structure of the extracellular portion of the beta chain of a murine T cell antigen receptor (TCR), determined at a… 
Highly Cited
1991
Highly Cited
1991
Internal initiation of translation in retroviral vectors carrying picornavirus 5' nontranslated regions
Previous work has shown that picornavirus 5' nontranslated regions (NTRs) can initiate internal translation of downstream coding… 
Highly Cited
1988
Highly Cited
1988
Single cell origin of bigenotypic and biphenotypic B cell proliferations in human follicular lymphomas
To investigate the possible relatedness of the subpopulations that make up so-called biclonal lymphomas, we examined five… 
Highly Cited
1987
Highly Cited
1987
Idiotype vaccination against murine B cell lymphoma. Humoral and cellular responses elicited by tumor-derived immunoglobulin M and its molecular subunits.
C3H/HeN mice were immunized with idiotypic immunoglobulin M (IgM) and its molecular subunits from the syngeneic 38C13 lymphoma… 
Highly Cited
1985
Highly Cited
1985
Cloning and expression of cDNA for salmon growth hormone in Escherichia coli.
cDNA clones encoding chum salmon (Oncorhynchus keta) growth hormone (sGH) have been isolated from a cDNA library prepared from… 
Highly Cited
1983
Highly Cited
1983
A common idiotope on human rheumatoid factors identified by a hybridoma antibody.
Highly Cited
1980
Highly Cited
1980
Hybridoma proteins expressing the predominant idiotype of the antiazophenylarsonate response of A/J mice.
Hybridoma cell lines that secrete monoclonal antiazophenylarsonate antibodies were isolated from the fusion of A/J splenic… 
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