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Complementarity Determining Regions
Known as:
Hypervariable Region, Immunoglobulin
, Regions, Complementarity-Determining
, Immunoglobulin Hypervariable Regions
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Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from…
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National Institutes of Health
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Related topics
Related topics
12 relations
Narrower (3)
Complementarity Determining Region 1
Complementarity Determining Region 2
Complementarity Determining Region 3
Immunoglobulin Heavy Chains
Immunoglobulin Light Chains
Immunoglobulin Variable Region
Immunoglobulin kappa-Chains
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1999
Highly Cited
1999
Analysis of the Critical Domain in the V3 Loop of Human Immunodeficiency Virus Type 1 gp120 Involved in CCR5 Utilization
C. Hung
,
N. Vander Heyden
,
L. Ratner
Journal of Virology
1999
Corpus ID: 24292098
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) infection of CD4+ lymphocytes and macrophages involves interaction of the…
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Highly Cited
1998
Highly Cited
1998
Independent induction of senescence by p16INK4a and p21CIP1 in spontaneously immortalized human fibroblasts.
M. Vogt
,
C. Haggblom
,
J. Yeargin
,
T. Christiansen-Weber
,
M. Haas
Cell growth & differentiation : the molecular…
1998
Corpus ID: 13290405
In this work, we address the question of whether replicative senescence can be induced in immortal nontumorigenic human…
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Highly Cited
1998
Highly Cited
1998
Collection, tumor contamination, and engraftment kinetics of highly purified hematopoietic progenitor cells to support high dose therapy in multiple myeloma.
G. Tricot
,
Y. Gazitt
,
+13 authors
B. Barlogie
Blood
1998
Corpus ID: 23469998
Unfractionated peripheral blood stem cell (PBSC) grafts contain measurable quantities of myeloma cells and are therefore a…
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Highly Cited
1995
Highly Cited
1995
Crystal structure of the beta chain of a T cell antigen receptor.
Graham A. Bentley
,
G. Boulot
,
Klaus Karjalainen
,
R. Mariuzza
Science
1995
Corpus ID: 31925748
The crystal structure of the extracellular portion of the beta chain of a murine T cell antigen receptor (TCR), determined at a…
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Highly Cited
1991
Highly Cited
1991
Internal initiation of translation in retroviral vectors carrying picornavirus 5' nontranslated regions
M. Adam
,
N. Ramesh
,
A D Miller
,
W. Osborne
Journal of Virology
1991
Corpus ID: 39816585
Previous work has shown that picornavirus 5' nontranslated regions (NTRs) can initiate internal translation of downstream coding…
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Highly Cited
1988
Highly Cited
1988
Single cell origin of bigenotypic and biphenotypic B cell proliferations in human follicular lymphomas
Michael L. Cleary
,
Naomi Galili
,
M. Trela
,
Ronald Levy
,
Jeffrey Sklar
Journal of Experimental Medicine
1988
Corpus ID: 1671665
To investigate the possible relatedness of the subpopulations that make up so-called biclonal lymphomas, we examined five…
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Highly Cited
1987
Highly Cited
1987
Idiotype vaccination against murine B cell lymphoma. Humoral and cellular responses elicited by tumor-derived immunoglobulin M and its molecular subunits.
Michael J. Campbell
,
William L. Carroll
,
+4 authors
Ronald Levy
Journal of Immunology
1987
Corpus ID: 44252294
C3H/HeN mice were immunized with idiotypic immunoglobulin M (IgM) and its molecular subunits from the syngeneic 38C13 lymphoma…
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Highly Cited
1985
Highly Cited
1985
Cloning and expression of cDNA for salmon growth hormone in Escherichia coli.
S. Sekine
,
Tamio Mizukami
,
+5 authors
Hiroshi Kawauchi
Proceedings of the National Academy of Sciences…
1985
Corpus ID: 43711843
cDNA clones encoding chum salmon (Oncorhynchus keta) growth hormone (sGH) have been isolated from a cDNA library prepared from…
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Highly Cited
1983
Highly Cited
1983
A common idiotope on human rheumatoid factors identified by a hybridoma antibody.
Dennis A. Carson
,
Sherman Fong
Molecular Immunology
1983
Corpus ID: 22462454
Highly Cited
1980
Highly Cited
1980
Hybridoma proteins expressing the predominant idiotype of the antiazophenylarsonate response of A/J mice.
Ann Marshak-Rothstein
,
M. Siekevitz
,
Michael N. MARGOLIESt
,
Meredith MUDGETT-HUNTERt
,
Malcolm L. Gefter
Proceedings of the National Academy of Sciences…
1980
Corpus ID: 6247781
Hybridoma cell lines that secrete monoclonal antiazophenylarsonate antibodies were isolated from the fusion of A/J splenic…
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