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Immunoglobulin Variable Region

Known as: Immunoglobulin Variable Region [Chemical/Ingredient], Regions, Immunoglobulin Variable, Variable Region, Ig 
That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
During HIV-1 infection, antibodies are generated against the region of the viral gp120 envelope glycoprotein that binds CD4, the… Expand
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Highly Cited
2008
Highly Cited
2008
Pre-existing neutralizing antibody provides the first line of defence against pathogens in general. For influenza virus, annual… Expand
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Highly Cited
2008
Highly Cited
2008
Lineage trees describe the microevolution of cells within an organism. They have been useful in the study of B cell affinity… Expand
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Highly Cited
2003
Highly Cited
2003
Activation-induced cytidine deaminase (AID), which is specific to B lymphocytes, is required for class switch recombination (CSR… Expand
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Highly Cited
2002
Highly Cited
2002
Although the presence or absence of somatic mutations in the immunoglobulin variable region (IgV(H)) genes in chronic lymphocytic… Expand
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Highly Cited
2002
Highly Cited
2002
A functional immune system depends on the production of a wide range of immunoglobulin molecules. Immunoglobulin variable region… Expand
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Highly Cited
2002
Highly Cited
2002
Most patients with follicular lymphoma (FL) have somatically mutated V genes with intraclonal variation, consistent with location… Expand
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Highly Cited
2001
Highly Cited
2001
B cell-derived chronic lymphocytic leukemia (B-CLL) represents a common malignancy whose cell derivation and pathogenesis are… Expand
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Highly Cited
2000
Highly Cited
2000
Clonal composition and T cell receptor (TCR) repertoire of CD4(+) and CD8(+) T cells infiltrating actively demyelinating multiple… Expand
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Highly Cited
1983
Highly Cited
1983
Transcriptional enhancers, originally discovered in viral genomes, are short, cis-acting, regulatory sequences that strongly… Expand
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