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Immunoglobulin Variable Region

Known as: Immunoglobulin Variable Region [Chemical/Ingredient], Regions, Immunoglobulin Variable, Variable Region, Ig 
That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific… 
National Institutes of Health

Related topics

Related topics

17 relations

Narrower (3)

1D4.1-325 DVD-Ig proteinComplementarity Determining RegionsFramework Region, Immunoglobulin
Binding Sites, AntibodyGene RearrangementImmunoglobulin DomainsImmunoglobulin Fv Fragments

Broader (1)

Immunologic Factors

Papers overview

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Highly Cited
1997
Highly Cited
1997
Diffuse large cell lymphomas are derived from mature B cells carrying V region genes with a high load of somatic mutation and evidence of selection for antibody expression
In the Revised European American Lymphoma (REAL) classification, several subtypes of high‐grade lymphomas were combined in the… 
Highly Cited
1995
Highly Cited
1995
Heavy chain variable region, light chain variable region, and heavy chain CDR3 influences on the mono- and polyreactivity and on the affinity of human monoclonal rheumatoid factors.
Monoreactive high affinity pathologic autoantibodies were supposed previously to derive through somatic mutation from… 
Highly Cited
1994
Highly Cited
1994
Mutational analysis of polymeric immunoglobulin receptor/ligand interactions. Evidence for the involvement of multiple complementarity determining region (CDR)-like loops in receptor domain I.
Review
1992
Review
1992
Selection of Immunoglobulin Variable Regions in Autoimmunity to DNA
Results from our analyses of variable region gene usage among spontaneous anti-DNA antibodies in autoimmune mice have indicated… 
Highly Cited
1988
Highly Cited
1988
Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4
Highly Cited
1987
Highly Cited
1987
The carcinoembryonic antigen (CEA) contains multiple immunoglobulin-like domains.
Highly Cited
1986
Highly Cited
1986
Recombination between immunoglobulin variable region gene segments is enhanced by transcription
Immunoglobulin (Ig) variable (V) region genes are assembled in precursor B (pre-B) lymphocytes from multiple germline segments… 
Highly Cited
1982
Highly Cited
1982
Translocation of immunoglobulin VH genes in Burkitt lymphoma.
We have produced cell hybrids between mouse myeloma cells, which do not produce immunoglobulin chains, and Burkitt lymphoma cells… 
Highly Cited
1977
Highly Cited
1977
Cloning of an immunoglobulin variable region gene from mouse embryo.
A 4.8-kilobase DNA fragment carrying an immunoglobulin gene coding for a mouse lambda chain variable region (Vlambda gene) was… 
Highly Cited
1975
Highly Cited
1975
Hypervariable regions, idiotypy, and the antibody-combining site.
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