Immunoglobulin Fv Fragments
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In recent years, there has been increasing interest in finding innovative solutions for the efficient removal of contaminants… Expand Purpose: Genetically altered cells could become widespread across the epithelium of patients with oral cancer, often in… Expand We generated a single chain Fv fragment of an antibody (scFv) with a binding affinity of about 5 pm to a short peptide by… Expand UNLABELLED
Prolonged clearance kinetics have hampered the development of intact antibodies as imaging agents, despite their… Expand Rapid production of protein-based tumor-specific vaccines for the treatment of malignancies is possible with the plant-based… Expand Crystallization of membrane proteins, a prerequisite for their X-ray crystallographic analysis, remains difficult. Here, we… Expand The facile detection and purification of a recombinant protein without detailed knowledge about its individual biochemical… Expand The formation of the disulfide bonds in the variable domains VH and VL of the antibody McPC603 was found to be essential for the… Expand Using X-ray coordinates of antigen-antibody complexes McPC 603, D1.3, and HyHEL-5, we made semiquantitative estimates of Gibbs… Expand An expression system was developed that allows the production of a completely functional antigen-binding fragment of an antibody… Expand