Gene Rearrangement

Known as: Rearrangements, DNA, Rearrangements, Gene, Gene Rearrangements 
Any DNA sequence rearrangement that results in the creation of a novel protein-coding capacity. Within certain genes, gene rearrangement is a normal… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Prostate cancer is the second most common cancer in men worldwide and causes over 250,000 deaths each year. Overtreatment of… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND ALK gene rearrangement defines a new molecular subtype of non-small-cell lung cancer (NSCLC). In a recent phase 1… (More)
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Highly Cited
2010
Highly Cited
2010
Individual variation in the Ig germline gene repertoire leads to individual differences in the combinatorial diversity of the Ab… (More)
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Highly Cited
2005
Highly Cited
2005
To gain more insight into initiation and regulation of T cell receptor (TCR) gene rearrangement during human T cell development… (More)
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Highly Cited
1997
Highly Cited
1997
The prognostic significance of Bcl-2 protein expression and bcl-2 gene rearrangement in diffuse large cell lymphomas (DLCL) is… (More)
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Highly Cited
1996
Highly Cited
1996
Productive gene rearrangement at the T-cell receptor (TCR) beta-chain locus facilitates formation of the "pre-TCR," a molecular… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND Translocations involving chromosome band 11q23 are very frequent in both acute lymphoblastic and acute myeloid… (More)
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Highly Cited
1991
Highly Cited
1991
Virus-transformed pre-B cells undergo ordered immunoglobulin (Ig) gene rearrangements during culture. We devised a series of… (More)
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Highly Cited
1989
Highly Cited
1989
We have developed a sensitive polymerase chain reaction assay for measuring the fraction of rearranged immunoglobulin kappa genes… (More)
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Highly Cited
1982
Highly Cited
1982
The first part of this article discusses the isolation and characterization of several monoclonal antibodies to the B lineage… (More)
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