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Gene Rearrangement

Known as: Rearrangements, DNA, Rearrangements, Gene, Gene Rearrangements 
Any DNA sequence rearrangement that results in the creation of a novel protein-coding capacity. Within certain genes, gene rearrangement is a normal… 
National Institutes of Health

Related topics

Related topics

21 relations
Antibody DiversityBCL2 Gene Rear Bld/T QlChromosomal translocationChromosome region 6q22 rearrangements:Find:Pt:Tiss:Doc:FISH

Broader (3)

ImmunogeneticsMolecular Genetics (discipline)Recombination, Genetic

Narrower (1)

Immunoglobulin Class Switching

Papers overview

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2001
2001
Detection of myeloperoxidase by flow cytometry in acute lymphoblastic leukaemias with BCR-ABL gene rearrangement
Detection of myeloperoxidase by flow cytometry in acute lymphoblastic leukaemias with BCR-ABL gene rearrangement 
1998
1998
Restricted TCR V α gene rearrangements in T cells recognizing an immunodominant peptide of myelin basic protein in DR 2 patients with multiple sclerosis
T cell responses to myelin basic protein (MBP) are thought to play an important role in the pathogenesis of multiple sclerosis… 
Highly Cited
1991
Highly Cited
1991
Absence of bcl-2 major breakpoint region and JH gene rearrangement in lymphocyte predominance Hodgkin's disease. Results of Southern blot analysis and polymerase chain reaction.
Recent evidence suggests that nodular lymphocyte predominance Hodgkin's disease (NLPHD) is a distinct entity that may be related… 
1991
1991
Methylation status of T-cell receptor beta-chain gene in B precursor acute lymphoblastic leukemia: correlation with hypomethylation and gene rearrangement.
Epigenetic changes may play a role in genetic alterations in cancer cells, but little is known about this phenomenon. In this… 
Highly Cited
1987
Highly Cited
1987
T-cell receptor gene rearrangement in regressing atypical histiocytosis.
A case of regressing atypical histiocytosis having characteristic clinical and light microscopic findings was studied… 
1987
1987
T cell gamma gene rearrangements in hematologic neoplasms.
Rearrangements of the T cell gamma (T gamma) gene were studied in primary neoplastic cells from 75 patients with leukemia or… 
1985
1985
Separation of lymphoid and myeloid blasts in the mixed blast crisis of chronic myelogenous leukemia: no evidence for Ig gene rearrangement in CALLA-positive blasts.
Recent studies suggest that lymphoid blast crisis cells of chronic myelogenous leukemia (CML) expressing the common acute… 
1985
1985
T-cell receptor gene rearrangement in a patient with common acute lymphocytic leukemia.
Using a beta-chain cDNA probe of the T-cell receptor, we detected T-cell receptor gene rearrangement in leukemic cells from an… 
1984
1984
Two-dimensional S1 nuclease heteroduplex mapping: detection of rearrangements in bacterial genomes.
A method of two-dimensional S1 nuclease heteroduplex mapping was developed to detect gene rearrangements and repeated sequences… 
1979
1979
The role of gene rearrangement in evolution.
Chromosomes are commonly regarded as conservative structures, in which an exact amount of genetic information is arranged in a…