Immunoglobulin Light Chains

Known as: Immunoglobulins, Light-Chain, Immunoglobulin Light Chains [Chemical/Ingredient], Light Chain Immunoglobulins 
Polypeptide chains, consisting of 211 to 217 amino acid residues and having a molecular weight of approximately 22 kDa. There are two major types of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Differentiating immunoglobulin light-chain (AL) from transthyretin-related cardiac amyloidoses (ATTR) is imperative… (More)
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Highly Cited
2012
Highly Cited
2012
PURPOSE To identify the criteria for hematologic and cardiac response to treatment in immunoglobulin light chain (AL) amyloidosis… (More)
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2009
2009
Amyloid diseases are characterized by the misfolding of a precursor protein that leads to amyloid fibril formation. Despite the… (More)
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Highly Cited
2008
Highly Cited
2008
Although the essential role of the adaptor protein SLP-65 in pre-B cell differentiation is established, the molecular mechanism… (More)
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Highly Cited
2005
Highly Cited
2005
Deletion of the gene encoding the Fc immunoglobulin G receptor IIB (FcγRIIB) results in a fulminant, lupus-like disease in C57BL… (More)
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Highly Cited
2003
Highly Cited
2003
Monoclonal immunoglobulin light chains are deposited as amyloid fibrils in systemic AL (primary) amyloidosis, but the underlying… (More)
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Highly Cited
2001
Highly Cited
2001
Light chain, or AL, amyloidosis is a pathological condition arising from systemic extracellular deposition of monoclonal… (More)
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Highly Cited
1999
Highly Cited
1999
The immunoglobulin (Ig) molecule is composed of two identical heavy chains and two identical light chains (H2L2). Transport of… (More)
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1999
1999
The most common form of systemic amyloidosis originates from antibody light chains. The large number of amino acid variations… (More)
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Highly Cited
1987
Highly Cited
1987
Previous studies have shown that the chicken lambda immunoglobulin light chain gene undergoes a single rearrangement that results… (More)
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