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Immunoglobulin Light Chains

Known as: Immunoglobulins, Light-Chain, Immunoglobulin Light Chains [Chemical/Ingredient], Light Chain Immunoglobulins 
Polypeptide chains, consisting of 211 to 217 amino acid residues and having a molecular weight of approximately 22 kDa. There are two major types of… 
National Institutes of Health

Related topics

Related topics

24 relations
Bence Jones ProteinBinding ProteinsComplementarity Determining RegionsGenes, Immunoglobulin Light Chain

Broader (1)

Immunologic Factors

Papers overview

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Highly Cited
2006
Highly Cited
2006
Control of gene conversion and somatic hypermutation by immunoglobulin promoter and enhancer sequences
It is thought that gene conversion (GCV) and somatic hypermutation (SHM) of immunoglobulin (Ig) genes occur in two steps: the… 
Highly Cited
1996
Highly Cited
1996
Re-evaluation of the probabilities for productive rearrangements on the κ andλloci
V-J rearrangements at Ig light chain (IgL) genes occur in resting small pre-B cells. In the absence of cell division, the… 
1996
1996
Structural peculiarities of a truncated VκIII immunoglobulin light chain in myeloma with light chain deposition disease
We report on the primary sequence of the monoclonal immunoglobulin light chain (LC) REV involved in myeloma‐associated light… 
Review
1993
Review
1993
Monoclonal immunoglobulin light chain-related renal diseases.
The spectrum of renal lesions associated with deposition of monoclonal light chains is varied and extensive, yet the simultaneous… 
Highly Cited
1993
Highly Cited
1993
Isolation of a shark immunoglobulin light chain cDNA clone encoding a protein resembling mammalian kappa light chains: implications for the evolution of light chains.
The time of emergence of immunoglobulin kappa and lambda light (L) chains in evolution is unknown. An L chain cDNA clone was… 
Highly Cited
1989
Highly Cited
1989
Complete nucleotide sequence of primitive vertebrate immunoglobulin light chain genes.
Antibody to Heterodontus francisci (horned shark) immunoglobulin light chain was used to screen a spleen cDNA expression library… 
Highly Cited
1982
Highly Cited
1982
Recombined flanks of the variable and joining segments of immunoglobulin genes.
The mechanism of generating immunoglobulin light chain genes by rearrangement of variable (V), joining (J), and constant (C) gene… 
Highly Cited
1980
Highly Cited
1980
Nodular glomerulopathy associated with nonamyloidotic kappa light chain deposits and excess immunoglobulin light chain synthesis.
A nodular glomerulopathy characterized by mesangial deposits of monoclonal kappa light chains was detected by immunofluorescence… 
Highly Cited
1979
Highly Cited
1979
Glucose-dependent glycosylation of secretory glycoprotein in mouse myeloma cells.
1970
1970
Electrophoretic distribution of kappa and lambda immunoglobulin light chain determinants in serum and cerebrospinal fluid in multiple sclerosis.
SUMMARY Theelectrophoretic distribution ofKappaandLambdalight chainantigenic determinants werestudied incerebrospinal fluid (CSF… 
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