Share This Author
Sequencing end-labeled DNA with base-specific chemical cleavages.
The genomic sequencing procedures are applicable to the analysis of genetic polymorphisms, DNA methylation at deoxycytidines, and nucleic acid-protein interactions at single nucleotide resolution.
The genetic data environment an expandable GUI for multiple sequence analysis
- Steven W. Smith, R. Overbeek, C. Woese, W. Gilbert, P. Gillevet
- Computer ScienceComput. Appl. Biosci.
- 1 December 1994
An X-Windows-based graphic user interface is presented which allows the seamless integration of numerous existing biomolecular programs into a single analysis environment. This environment is based…
Origin of life: The RNA world
- W. Gilbert
- 20 February 1986
L'auteur postule un systeme, auto-replicatif a l'origine uniquement compose de molecules d'ARN.
Nucleotide sequence of rous sarcoma virus
A new method for sequencing DNA.
- A. Maxam, W. Gilbert
- Biology, ChemistryProceedings of the National Academy of Sciences…
- 1 February 1977
Reactions that cleave DNA preferentially at guanines, at adenines,At cytosines and thymines equally, and at cytosine alone are described.
Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis
It is speculated that this self-recognition of guanine-rich motifs of DNA serves to bring together, and to zipper up in register, the four homologous chromatids during meiosis.
The evolution of spliceosomal introns: patterns, puzzles and progress
Patterns of intron-position correspondence between widely diverged eukaryotic species have provided insights into the origins of the vast differences in intron number between eukARYotic species, and studies of specific cases of introns loss and gain have led to progress in understanding the underlying molecular mechanisms and the forces that control intron evolution.
Large-scale comparison of intron positions in mammalian genes shows intron loss but no gain
The finding of widespread conservation of intron–exon structure, even over large evolutionary distances, suggests that comparative methods employing information about gene structures should be very successful in correctly predicting exon boundaries in genomic sequences.