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Complementarity Determining Region 2

Known as: Complementarity Determining Region II 
National Institutes of Health

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Complementarity Determining Regions

Papers overview

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2011
2011
Development of a genetically-modified novel T-cell receptor for adoptive cell transfer against renal cell carcinoma.
2010
2010
Cloning and characterization of a single-chain fragment of monoclonal antibody to ACE suitable for lung endothelial targeting.
2002
2002
Immunoglobulin diversification in B cell malignancies: internal splicing of heavy chain variable region as a by-product of somatic hypermutation
In this study we describe alternative splicing of somatically mutated immunoglobulin (Ig) variable heavy chain (VH) genes in… 
2000
2000
Mapping the Energy of Superantigen Staphylococcus Enterotoxin C3 Recognition of an α/β T Cell Receptor Using Alanine Scanning Mutagenesis
Binding of the T cell receptor (TCR) to a bacterial superantigen (SAG) results in stimulation of a large population of T cells… 
1996
1996
Tolerance of single, but not multiple, amino acid replacements in antibody VH CDR 2: a means of minimizing B cell wastage from somatic hypermutation?
Mutations in the heavy chain complementarity determining region 2 (CDR2) of the phosphocholine-specific T15 Ab can have a… 
1994
1994
Inhibition of human T-cell responses to house dust mite allergens by a T-cell receptor peptide.
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