Immunoglobulin kappa-Chains

Known as: Ig Light Chain Kappa, Immunoglobulin kappa-Chain, chain kappa light 
Immunoglobulin Light Chain Kappa is one of two Ig light chain types. Each Ig molecule is typically composed of two heavy chains and two light chains… (More)
National Institutes of Health

Related topics

Related topics

17 relations
Binding ProteinsComplementarity Determining RegionsHumoral ImmunityIGK gene
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Broader (1)

Immunologic Factors

Narrower (2)

amyloid protein GRA, humanmyeloma-associated membrane antigen KMA

Papers overview

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Highly Cited
2003
Highly Cited
2003
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor.
The biochemical properties of beclin 1 suggest a role in two fundamentally important cell biological pathways: autophagy and… (More)
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Review
2000
Review
2000
The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling.
NF-kappa B is a heterodimeric transcription factor that plays a key role in inflammatory and immune responses. In nonstimulated… (More)
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Highly Cited
1995
Highly Cited
1995
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation.
I kappa B-alpha inhibits transcription factor NF-kappa B by retaining it in the cytoplasm. Various stimuli, typically those… (More)
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Highly Cited
1995
Highly Cited
1995
Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli.
Post-translational activation of the higher eukaryotic transcription factor NF-kappa B requires both phosphorylation and… (More)
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Highly Cited
1993
Highly Cited
1993
NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway.
The eukaryotic transcription factor nuclear factor-kappa B (NF-kappa B) participates in many parts of the genetic program… (More)
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Highly Cited
1989
Highly Cited
1989
A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins.
Two cDNAs were isolated whose dimerized products bind specifically to a DNA sequence, kappa E2, located in the immunoglobulin… (More)
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Highly Cited
1989
Highly Cited
1989
Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription
We have developed a sensitive polymerase chain reaction assay for measuring the fraction of rearranged immunoglobulin kappa genes… (More)
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Highly Cited
1988
Highly Cited
1988
I kappa B: a specific inhibitor of the NF-kappa B transcription factor.
In cells that do not express immunoglobulin kappa light chain genes, the kappa enhancer binding protein NF-kappa B is found in… (More)
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Highly Cited
1986
Highly Cited
1986
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
To characterize proteins that bind to the immunoglobulin (Ig) heavy chain and the kappa light chain enhancers, an electrophoretic… (More)
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Highly Cited
1986
Highly Cited
1986
Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites
Introduction of torsional stress into active chromatin domains requires that linear DNA molecules be anchored in vivo to impede… (More)
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