IGK gene

Known as: Immunoglobulin Kappa Locus, IGK@, Kappa Light Chain Gene 
This region represents the germline organization of the kappa light chain locus. The locus includes V (variable), J (joining), and C (constant… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
The BCR-ABL1 kinase expressed in acute lymphoblastic leukemia (ALL) drives malignant transformation of pre-B cells and prevents… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Immunoglobulin (Ig) and T cell receptor (TCR) genes are assembled during lymphocyte maturation through site-specific V(D)J… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Immunoglobulin (Ig)M+IgD+ B cells are generally assumed to represent antigen-inexperienced, naive B cells expressing variable (V… (More)
  • figure 1
  • table 1
  • table 1
  • figure 3
  • table 2
Is this relevant?
Highly Cited
1996
Highly Cited
1996
A novel Hodgkin's disease (HD) derived cell line, L1236, was established from the peripheral blood of a patient with advanced… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 6
Is this relevant?
Highly Cited
1995
Highly Cited
1995
A functional B cell antigen receptor is thought to regulate antibody gene rearrangement either by stopping further rearrangement… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
Is this relevant?
1993
1993
An analysis of cell lines representing different stages of the B-cell differentiation pathway indicated that about 50% of the… (More)
Is this relevant?
Highly Cited
1987
Highly Cited
1987
We have located presumptive chromosomal loop anchorage elements within the mouse heavy chain immunoglobulin locus. Analysis of 31… (More)
Is this relevant?
Highly Cited
1986
Highly Cited
1986
Introduction of torsional stress into active chromatin domains requires that linear DNA molecules be anchored in vivo to impede… (More)
Is this relevant?
Highly Cited
1984
Highly Cited
1984
We have created mouse-human antibody molecules of defined antigen-binding specificity by taking the variable region genes of a… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1983
Highly Cited
1983
We have examined the nucleotide sequences of a series of murine antibody genes derived from one kappa light chain gene in order… (More)
Is this relevant?