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Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance.
Mice Lacking p21 CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene
Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.
A convenient technique for the partial purification of large quantities of functional, poly(adenylic acid)-rich mRNA is described and should prove generally useful as an initial step in the isolation of specific mRNAs.
Fibroblast Growth Factor Receptor 3 Is a Negative Regulator of Bone Growth
Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction.
Findings provide direct genetic evidence that FGF/FGFR2 signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction.
Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor
Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo
Murine FGFR-1 is required for early postimplantation growth and axial organization.
- C. Deng, A. Wynshaw-Boris, M. Shen, C. Daugherty, D. Ornitz, P. Leder
- BiologyGenes & development
- 15 December 1994
It is demonstrated that FGFR-1 is required for proper embryonic cell proliferation and for the correct axial organization of early postimplantation embryos but not for mesoderm formation.