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CD19-specific chimeric antigen receptor

Known as: CAR19 protein 
National Institutes of Health

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Related topics

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Broader (1)

T-Cell Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract PR10: Enhancing the efficacy of T cell-based immunotherapies using miR-155 engineered tumor-specific CD8+ T cells
Lymphodepleting regimens are employed prior to adoptive immunotherapy to augment the antitumor efficacy of transferred T cells by… 
Highly Cited
2016
Highly Cited
2016
Generation of clinical-grade CD19-specific CAR-modified CD8+ memory stem cells for the treatment of human B-cell malignancies.
Long-lived, self-renewing, multipotent T memory stem cells (TSCM) can trigger profound and sustained tumor regression but their… 
2014
2014
The Tol2 transposon system mediates the genetic engineering of T-cells with CD19-specific chimeric antigen receptors for B-cell malignancies
Engineered T-cell therapy using a CD19-specific chimeric antigen receptor (CD19-CAR) is a promising strategy for the treatment of… 
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