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ALT-801

Known as: IL-2 Recombinant Fusion Protein ALT-801 
A recombinant protein consisting of the cytokine interleukin-2 (IL-2) fused to a humanized soluble T-cell receptor (TCR) directed against a tumor… Expand
National Institutes of Health

Papers overview

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2015
2015
451 Background: Novel agents are necessary to treat BCG-resistant NMIBC to avoid radical cystectomy (RC). This phase I clinical… Expand
2015
2015
4515 Background: Although UC is sensitive to platinum-based chemotherapy such as gemcitabine (G) + cisplatin (C), patients who… Expand
2014
2014
ALT-801, a fusion of interleukin-2 and a single-chain T cell receptor domain specific to a p53 peptide/HLA-A*0201 complex, has… Expand
2013
2013
271 Background: ALT-801, a T-cell receptor/IL-2 fusion protein, activates NK and CD4+ lymphocytes to secrete IFN-gamma which re… Expand
2012
2012
ALT-801 is a fusion protein between interleukin-2 and a T cell receptor domain capable of recognizing tumors presenting human p53… Expand
2011
2011
Purpose: ALT-801 is a bifunctional fusion protein comprising interleukin-2 (IL-2) linked to a soluble, single-chain T-cell… Expand
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2010
2010
(-)-Epigallocatechin gallate, Abafungin, ACE-031, Adapalene/benzoyl peroxide, AE-37, Aflibercept, AGS-003, Albiglutide… Expand
2009
2009
3040 Background: ALT-801 is recombinant human interleukin-2 (IL-2) genetically fused to a single-chain T-cell receptor specific… Expand