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CD3 Antigens

Known as: CD3 Antigen, Antigen, T3, CD3 Complex 
Consisting of cell surface type I membrane Delta, Epsilon, Gamma, Zeta, and Eta protein subunits with ITAM domains and noncovalently associated with… 
National Institutes of Health

Related topics

Related topics

17 relations

Broader (2)

Antigens, Differentiation, T-LymphocyteCD Antigens
CD3 Ag:PrThr:Pt:Tiss:Ord:Immune stainCD3D protein, humanCD3E geneIn Blood

Narrower (3)

CD3 antigen, gamma chainCD3E protein, humanCD3delta antigen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
The expression of TCR-gamma delta/CD3 complex in neoplastic gamma delta T-cell.
We describe that the neoplastic gammadelta T-cells from patients with hepatosplenic gammadelta T-cell lymphoma have a lower… 
2002
2002
Sequencing and expression of the CD3 γ/δ mRNA in Pleurodeles waltl (urodele amphibian)
Abstract. The CD3 complex is an essential component of the T-cell receptor (TCR) implicated in T-cell maturation and activation… 
2000
2000
Immunolabeling of CD3-Positive Lymphocytes with a Recombinant Single-Chain Antibody/Alkaline Phosphatase Conjugate
Abstract G3(3) is a novel murine monoclonal antibody directed against the CD3 antigen of human T lymphocytes which could be used… 
Review
1999
Review
1999
Expression of A 2 B adenosine receptors in human lymphocytes : their role in T cell activation
Adenosine, acting outside the cell, exerts potent actions on a wide variety of physiological systems, including the nervous… 
1999
1999
Regulation of T cell receptor ( TCR ) b gene expression by CD 3 complex signaling in immature thymocytes : Implications for TCR b allelic exclusion
During ab thymocyte development, clonotype-independent CD3 complexes are expressed at the cell surface before the pre-T cell… 
1998
1998
Expression of a CD 3 ε transgene in CD 3 ε null mice does not restore CD 3 γ and δ expression but efficiently rescues T cell development from a subpopulation of prothymocytes
The TCR-associated CD3 complex consists of four subunits, i.e. CD3 γ, δ, ε and ζ, which are expressed very early in T cell… 
1989
1989
Evidence that a kinase distinct from protein kinase C induces CD3 gamma-subunit phosphorylation without a concomitant down-regulation in CD3 antigen expression.
An immediate consequence of Ag-specific activation of T cells is phosphorylation of the gamma-subunit of the CD3 gamma-chain… 
1986
1986
Isolation of cDNA clones encoding the 20K non-glycosylated polypeptide chain of the human T-cell receptor/T3 complex
Nature 321, 431–434 (1986). THREE sequencing errors have been found in the human T3-e nucleotide sequence published in Fig. 3b… 
1985
1985
Phorbol ester induces a differential effect on the effector function of human allospecific cytotoxic T lymphocyte and natural killer clones.
Six-day allosensitized human peripheral blood lymphocytes treated for 12-18 hr with phorbol 12-myristate 13-acetate (PMA) were… 
Review
1985
Review
1985
The role of the T3 molecular complex on human T lymphocyte-mediated cytotoxicity.
The above overview of the experimental data clearly indicates that the T3 molecular complex is intimately involved in T cell…