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1-nitropyrene

Known as: 1-NP, 3-nitropyrene 
A synthetic, light sensitive, yellow crystalline solid that is practically insoluble in water and soluble in diethyl ether, acetone, ethanol, benzene… 
National Institutes of Health

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2 relations

Broader (2)

MutagensPyrenes

Papers overview

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Highly Cited
1999
Highly Cited
1999
Advantage of the use of human liver S9 in the Ames test.
Highly Cited
1999
Highly Cited
1999
Polycyclic nitroarenes (nitro-PAHs) as biomarkers of exposure to diesel exhaust.
Highly Cited
1999
Highly Cited
1999
The DNA repair inhibitors hydroxyurea and cytosine arabinoside enhance the sensitivity of the alkaline single-cell gel electrophoresis ('comet') assay in metabolically-competent MCL-5 cells.
Highly Cited
1987
Highly Cited
1987
Assay of 1-nitropropane, 2-nitropropane, 1-azoxypropane and 2-azoxypropane for carcinogenicity by gavage in Sprague-Dawley rats.
1-Nitropropane (1-NP), 2-nitropropane (2-NP), 1-azoxypropane (1-AP) and 2-azoxypropane (2-AP), were assayed for carcinogenicity… 
Highly Cited
1986
Highly Cited
1986
Ubiquitous occurrence of 2-nitrofluoranthene and 2-nitropyrene in air
Several nitrated polycyclic aromatic hydrocarbons (nitro-PAH) are direct-acting mutagens1,2 and/or carcinogens2–4, and are… 
Highly Cited
1985
Highly Cited
1985
Mutagenic/carcinogenic agents in indoor pollutants; the dinitropyrenes generated by kerosene heaters and fuel gas and liquefied petroleum gas burners.
Highly Cited
1984
Highly Cited
1984
Induction of rat mammary gland tumors by 1-nitropyrene, a recently recognized environmental mutagen.
1-Nitropyrene, a direct-acting mutagenic component of extracts of diesel exhaust and ambient air particulates, is one of the… 
Highly Cited
1983
Highly Cited
1983
Formation of DNA adducts in vitro and in Salmonella typhimurium upon metabolic reduction of the environmental mutagen 1-nitropyrene.
The polycyclic nitroaromatic hydrocarbon 1-nitropyrene is an environmental pollutant, a potent bacterial mutagen, and a… 
Highly Cited
1983
Highly Cited
1983
Identification and mutagenicity of metabolites of 1-nitropyrene formed by rat liver.
The metabolism of 1-nitropyrene by rat liver 9000 X g supernatant was investigated. Under aerobic conditions, ring oxidation to 1… 
Highly Cited
1981
Highly Cited
1981
Metabolism of 1-nitropyrene and formation of DNA adducts in Salmonella typhimurium.
1-Nitropyrene is slowly reduced by intact cells of Salmonella typhimurium to yield 1-aminopyrene and N-acetyl-1-aminopyrene plus… 
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