FAQ

Mutagens

Known as: Genotoxins, Mutagen 
Anything that causes a mutation (a change in the DNA of a cell). DNA changes caused by mutagens may harm cells and cause certain diseases, such as… (More)

Topic mentions per year

Topic mentions per year

1947-2018
020040019472017

Related topics

Related topics

50 relations

Narrower (42)

1,3-dichloro-2-propanol1,6-dinitropyrene1-nitropyrene2'-deoxyadenosine
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Alkylating AgentsAntimitotic AgentsCarcinogensDNA Adducts
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Related mentions per year

Related mentions per year

1939-2018
19401960198020002020
Mutagens
Carcinogens
Alkylating Agents
Ethidium
DNA Adducts
Acridine Orange

Papers overview

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Highly Cited
2003
Highly Cited
2003
Cadmium is a mutagen that acts by inhibiting mismatch repair
Most errors that arise during DNA replication can be corrected by DNA polymerase proofreading or by post-replication mismatch… (More)
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Highly Cited
2000
Highly Cited
2000
The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen
The ribonucleoside analog ribavirin (1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) shows antiviral activity against a variety… (More)
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Highly Cited
2000
Highly Cited
2000
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA.
Spontaneous oxidation of guanine residues in DNA generates 8-oxoguanine (oxoG). By mispairing with adenine during replication… (More)
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Highly Cited
1991
Highly Cited
1991
A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.
Sunlight is a carcinogen to which everyone is exposed. Its UV component is the major epidemiologic risk factor for squamous cell… (More)
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Highly Cited
1983
Highly Cited
1983
Revised methods for the Salmonella mutagenicity test.
The methods for detecting carcinogens and mutagens with the Salmonella mutagenicity test were described previously (Ames et al… (More)
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Highly Cited
1975
Highly Cited
1975
Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange.
A staining technique that detects sister chromatid exchanges (SCEs) has been used to examine the response of chromosomes in… (More)
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Highly Cited
1975
Highly Cited
1975
Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.
We described previously a simple test on petri plates for detecting chemical carcinogens as mutagens, using an especially… (More)
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Highly Cited
1975
Highly Cited
1975
Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.
 
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Highly Cited
1973
Highly Cited
1973
Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection.
18 Carcinogens, including aflatoxin B(1), benzo(a)pyrene, acetylaminofluorene, benzidine, and dimethylamino-trans-stilbene, are… (More)
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Highly Cited
1973
Highly Cited
1973
An improved bacterial test system for the detection and classification of mutagens and carcinogens.
We previously described a set of four strains of Salmonella typhimurium designed for detecting the various types of mutagens, and… (More)
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