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Mutagens

Known as: Genotoxins, Mutagen 
Anything that causes a mutation (a change in the DNA of a cell). DNA changes caused by mutagens may harm cells and cause certain diseases, such as… Expand
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (44)

1,3-butadiene1,3-dichloro-2-propanol1,3-dinitropyrene1,N(6)-ethenoadenine
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Alkylating AgentsAntimitotic AgentsIntercalating AgentsMutagenesis Process
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Broader (1)

Pharmaceutical Preparations

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
The SOS system: A complex and tightly regulated response to DNA damage
Genomes of all living organisms are constantly threatened by endogenous and exogenous agents that challenge the chemical… Expand
Review
2018
Review
2018
Danger-Associated Molecular Patterns (DAMPs): the Derivatives and Triggers of Inflammation
  • S. Patel
  • Current Allergy and Asthma Reports
  • 2018
    • Corpus ID: 52883240
Purpose of ReviewAllergen is an umbrella term for irritants of diverse origin. Along with other offenders such as pathogens… Expand
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Review
2018
Review
2018
Carcinogens and DNA damage
Humans are variously and continuously exposed to a wide range of different DNA-damaging agents, some of which are classed as… Expand
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Review
2018
Review
2018
The Eye, Oxidative Damage and Polyunsaturated Fatty Acids
Polyunsaturated fatty acids (PUFA) are known to have numerous beneficial effects, owing to their anti-inflammatory and… Expand
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Review
2017
Review
2017
Mechanisms of DNA damage, repair, and mutagenesis
Living organisms are continuously exposed to a myriad of DNA damaging agents that can impact health and modulate disease‐states… Expand
Review
2017
Review
2017
Microbiota, Inflammation and Colorectal Cancer
Colorectal cancer, the fourth leading cause of cancer-related death worldwide, is a multifactorial disease involving genetic… Expand
Highly Cited
1975
Highly Cited
1975
Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.
We describe in this paper the general methods for using the Salmonella/microsome test as a mutagenesis screening system. The… Expand
Highly Cited
1975
Highly Cited
1975
Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.
About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple… Expand
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Highly Cited
1973
Highly Cited
1973
Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection.
18 Carcinogens, including aflatoxin B(1), benzo(a)pyrene, acetylaminofluorene, benzidine, and dimethylamino-trans-stilbene, are… Expand
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Highly Cited
1973
Highly Cited
1973
An improved bacterial test system for the detection and classification of mutagens and carcinogens.
We previously described a set of four strains of Salmonella typhimurium designed for detecting the various types of mutagens, and… Expand
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