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Mutagens

Known as: Genotoxins, Mutagen 
Anything that causes a mutation (a change in the DNA of a cell). DNA changes caused by mutagens may harm cells and cause certain diseases, such as… 
National Institutes of Health

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Narrower (44)

1,3-butadiene1,3-dichloro-2-propanol1,3-dinitropyrene1,N(6)-ethenoadenine
Alkylating AgentsAntimitotic AgentsIntercalating AgentsMutagenesis Process

Broader (1)

Pharmaceutical Preparations

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1993
Highly Cited
1993
DNA adduct-induced stabilization of slipped frameshift intermediates within repetitive sequences: implications for mutagenesis.
Chemical carcinogens such as the aromatic amide 2-acetylaminofluorene (AAF) are known to induce -1 frameshift mutation hotspots… 
Highly Cited
1985
Highly Cited
1985
Modification of chromium(VI)-induced DNA damage by glutathione and cytochromes P-450 in chicken embryo hepatocytes.
The role of glutathione and cytochrome P-450 in the production of DNA damage by chromium(VI) was examined in chicken embryo… 
Highly Cited
1984
Highly Cited
1984
Induction of rat mammary gland tumors by 1-nitropyrene, a recently recognized environmental mutagen.
1-Nitropyrene, a direct-acting mutagenic component of extracts of diesel exhaust and ambient air particulates, is one of the… 
Highly Cited
1983
Highly Cited
1983
Formation of DNA adducts in vitro and in Salmonella typhimurium upon metabolic reduction of the environmental mutagen 1-nitropyrene.
The polycyclic nitroaromatic hydrocarbon 1-nitropyrene is an environmental pollutant, a potent bacterial mutagen, and a… 
Highly Cited
1983
Highly Cited
1983
Mutagen treatment as a means for selecting immunogenic variants from otherwise poorly immunogenic malignant murine tumors.
The selection of nontumorigenic (tum-), highly immunogenic variants from four different tumorigenic but poorly immunogenic murine… 
Highly Cited
1981
Highly Cited
1981
Evaluation of the release of mutagens from diesel particles in the presence of physiological fluids.
The Ames Salmonella typhimurium plate incorporation assay was used to evaluate the mutagenicity of organics extracted from diesel… 
Highly Cited
1980
Highly Cited
1980
A sensitive hepatocyte-mediated assay for the metabolism of nitrosamines to mutagens for mammalian cells.
A sensitive cell-mediated assay has been developed for testing mutagenesis in Chinese hamster V79 cells by carcinogenic… 
Highly Cited
1978
Highly Cited
1978
Role of arylhydroxamic acid acyltransferase in the mutagenicity of N-hydroxy-N-2-fluorenylacetamide in Salmonella typhimurium.
Abstract Partially purified fractions of rat liver arylhydroxamic acid acyltransferase were used as the external metabolic… 
Highly Cited
1977
Highly Cited
1977
Mutagen-nucleic acid intercalative binding: structure of a 9-aminoacridine: 5-iodocytidylyl(3'-5')guanosine crystalline complex.
9-Aminoacridine forms a crystalline complex with the dinucleoside monophosphate, 5-iodocytidylyl(3'-5')guanosine. We have solved… 
Highly Cited
1965
Highly Cited
1965
INDUCED MITOTIC CROSSING-OVER IN RELATION TO GENETIC REPLICATION IN SYNCHRONOUSLY DIVIDING CELLS OF USTILAGO MAYDIS.
A method is now available for synchronizing the division of populations of cells of the smut fungus Ustilago maydis . In two… 
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