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Intercalating Agents

Known as: Intercalating Agent, Intercalating Ligands, Ligands, Intercalating 
Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore… 
National Institutes of Health

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1,10-phenanthroline9-amino-6-chloro-2-methoxyacridineAcriflavineAmsacrine
Mutagensaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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2007
2007
Encapsulation of Anionic Dye Molecules by a Swelling Fluoromica through Intercalation of Cationic Polyelectrolytes
To develop a novel layered host material with the ability to encapsulate anionic substances, the intercalation of three cationic… 
Highly Cited
1993
Highly Cited
1993
DNA adduct-induced stabilization of slipped frameshift intermediates within repetitive sequences: implications for mutagenesis.
Chemical carcinogens such as the aromatic amide 2-acetylaminofluorene (AAF) are known to induce -1 frameshift mutation hotspots… 
Highly Cited
1987
Highly Cited
1987
Molecular modelling of the interactions of tetra-(4-N-methylpyridyl) porphin with TA and CG sites on DNA.
The molecular structure of the DNA-intercalating ligand tetra-(4-N-methylpyridyl) porphin has been determined by X-ray… 
1985
1985
Effect of difluoromethylornithine, an inhibitor of polyamine biosynthesis, on the topoisomerase II-mediated DNA scission produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide in L1210 murine…
Treatment of mouse leukemia L1210 cells with the polyamine biosynthesis inhibitor alpha-difluoromethylornithine (DFMO) increased… 
Highly Cited
1984
Highly Cited
1984
Changes in deoxyribonucleic acid linking number due to treatment of mammalian cells with the intercalating agent 4'-(9-acridinylamino)methanesulfon-m-anisidide.
Treatment of mammalian cells with DNA intercalating agents produces protein-associated DNA strand breaks. These breaks have been… 
1984
1984
The solvation contribution to the binding energy of DNA with non-intercalating antibiotics.
The influence of the solvent on the binding energies to DNA of six non-intercalating antibiotics - netropsin, distamycin-3… 
1984
1984
Binding of ethidium and bis(methidium)spermine to Z DNA by intercalation.
The interaction of ethidium bromide, a DNA intercalating drug, and bis( methidium )spermine, a DNA bis-intercalating compound… 
1982
1982
Molecular pharmacology of the anthracycline drug 9,10-anthracenedicarboxaldehyde bis[(4,5-dihydro-1 H-imidazol-2-yl)hydrazone] dihydrochloride (Cl 216,942).
9,10-Anthracenedicarboxyaldehyde bis[(4,5-dihydro-1H-imidazol-2yl)hydrazone] dihydrochloride (Cl 216,942) is a new anthracene… 
1980
1980
Binding of quinoline analogues of echinomycin to deoxyribonucleic acid. Role of the chromophores.
Two novel antibiotics were isolated, designated compounds 1QN and 2QN respectively, having quinoline rings in place of one or… 
Highly Cited
1979
Highly Cited
1979
Deoxyribonucleic acid bifunctional intercalators: kinetic investigation of the binding of several acridine dimers to deoxyribonucleic acid.