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Intercalating Agents

Known as: Intercalating Agent, Intercalating Ligands, Ligands, Intercalating 
Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore… 
National Institutes of Health

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1,10-phenanthroline9-amino-6-chloro-2-methoxyacridineAcriflavineAmsacrine
Mutagensaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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2002
2002
CAFFEINE AND OTHER XANTHINES AS CYTOCHEMICAL BLOCKERS AND REMOVERS OF HETEROCYCLIC DNA INTERCALATORS FROM CHROMATIN
Caffeine (CAF) and other xanthines non‐covalently bind with the cationic fluorescent dye acridine orange (AO) and with other… 
1986
1986
Circular differential scattering and circular differential absorption of DNA-protein condensates and of dyes bound to DNA-protein condensates.
DNA-protein condensates that give positive and negative psi-type circular dichroism (CD) spectra (psi condensates) bind… 
1984
1984
The solvation contribution to the binding energy of DNA with non-intercalating antibiotics.
The influence of the solvent on the binding energies to DNA of six non-intercalating antibiotics - netropsin, distamycin-3… 
Highly Cited
1984
Highly Cited
1984
Changes in deoxyribonucleic acid linking number due to treatment of mammalian cells with the intercalating agent 4'-(9-acridinylamino)methanesulfon-m-anisidide.
Treatment of mammalian cells with DNA intercalating agents produces protein-associated DNA strand breaks. These breaks have been… 
1984
1984
Binding of ethidium and bis(methidium)spermine to Z DNA by intercalation.
The interaction of ethidium bromide, a DNA intercalating drug, and bis( methidium )spermine, a DNA bis-intercalating compound… 
1982
1982
Molecular pharmacology of the anthracycline drug 9,10-anthracenedicarboxaldehyde bis[(4,5-dihydro-1 H-imidazol-2-yl)hydrazone] dihydrochloride (Cl 216,942).
9,10-Anthracenedicarboxyaldehyde bis[(4,5-dihydro-1H-imidazol-2yl)hydrazone] dihydrochloride (Cl 216,942) is a new anthracene… 
1980
1980
Binding of quinoline analogues of echinomycin to deoxyribonucleic acid. Role of the chromophores.
Two novel antibiotics were isolated, designated compounds 1QN and 2QN respectively, having quinoline rings in place of one or… 
Highly Cited
1979
Highly Cited
1979
Deoxyribonucleic acid bifunctional intercalators: kinetic investigation of the binding of several acridine dimers to deoxyribonucleic acid.
1978
1978
Synthesis, DNA-binding and biological activity of a double intercalating analog of ethidium bromide.
A bis-phenanthridinium salt has been synthesized and its DNA-binding studied. Evidence provided by UV and CD spectra, by thermal… 
Review
1976
Review
1976
Mechanisms and selectivity of anthracycline aminoglycosides and other intercalating agents.
: Many of the antiproliferative actions of daunorubicin and adriamycin are attributable to the results of their interaction with…