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Intercalating Agents

Known as: Intercalating Agent, Intercalating Ligands, Ligands, Intercalating 
Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore… 
National Institutes of Health

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1,10-phenanthroline9-amino-6-chloro-2-methoxyacridineAcriflavineAmsacrine
Mutagensaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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Highly Cited
2008
Highly Cited
2008
Synthesis, characterization, DNA-binding study and anticancer properties of ternary metal(II) complexes of edda and an intercalating ligand.
A series of ternary metal(ii) complexes {M(phen)(edda); 1a (Cu), 1b (Co), 1c (Zn), 1d (Ni); H(2)edda = N,N… 
Highly Cited
2007
Highly Cited
2007
Microcalorimetry of interaction of dihydro-imidazo-phenanthridinium (DIP)-based compounds with duplex DNA.
Review
2005
Review
2005
Intercalation of Organic Dye Molecules into Double-stranded DNA. Part 2: The Annelated Quinolizinium Ion as a Structural Motif in DNA Intercalators†
Abstract DNA intercalators represent an important class of compounds with a high potential as DNA-targeting drugs. In this review… 
Highly Cited
2005
Highly Cited
2005
Label-free impedance detection of oligonucleotide hybridisation on interdigitated ultramicroelectrodes using electrochemical redox probes.
Highly Cited
2002
Highly Cited
2002
DNA binding of an ethidium intercalator attached to a monolayer-protected gold cluster.
Ethidium intercalation has been investigated as a means of inducing binding of Au nanoparticles to DNA. The ethidium sites are… 
Highly Cited
1998
Highly Cited
1998
Immobilization of single-stranded deoxyribonucleic acid on gold electrode with self-assembled aminoethanethiol monolayer for DNA electrochemical sensor applications.
Highly Cited
1989
Highly Cited
1989
A premelting conformational transition in poly(dA)-Poly(dT) coupled to daunomycin binding.
Circular dichroism and UV absorbance spectroscopy were used to monitor and characterize a premelting conformational transition of… 
Highly Cited
1989
Highly Cited
1989
Sequence-specific intercalating agents: intercalation at specific sequences on duplex DNA via major groove recognition by oligonucleotide-intercalator conjugates.
An acridine derivative was covalently linked to the 5' end of a homopyrimidine oligonucleotide. Specific binding to a homopurine… 
Highly Cited
1987
Highly Cited
1987
Enzymatic amplification of translation inhibition of rabbit beta-globin mRNA mediated by anti-messenger oligodeoxynucleotides covalently linked to intercalating agents.
The effects of anti-messenger oligodeoxynucleotides, covalently linked to an intercalating agent, on translation of rabbit beta… 
Review
1984
Review
1984
Physico-chemical probes of intercalation.
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