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  • W. Bonner, C. Redon, +4 authors Y. Pommier
  • Biology, Medicine
  • Nature Reviews Cancer
  • 2008 (First Publication: 13 November 2008)
  • Histone H2AX phosphorylation on a serine four residues from the carboxyl terminus (producing γH2AX) is a sensitive marker for DNA double-strand breaks (DSBs). DSBs may lead to cancer but,Expand
  • Yves Pommier
  • Biology, Medicine
  • ACS chemical biology
  • 2013 (First Publication: 18 January 2013)
  • Topoisomerases are ubiquitous enzymes that control DNA supercoiling and entanglements. They are essential during transcription and replication, and topoisomerase inhibitors are among the mostExpand