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Antimitotic Agents

Known as: mitotic inhibitor, Mitosis Inhibitors, Mitosis Inhibitor Drugs 
An agent that inhibits tumor growth by interfering with mitotic processes or the assembly of the mitotic machinery.
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Poly (ADP-ribose) polymerases (PARPs) play an important role in various cellular processes, such as replication, recombination… Expand
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Highly Cited
2008
Highly Cited
2008
Drugs targeting the mitotic spindle are used extensively during chemotherapy, but surprisingly, little is known about how they… Expand
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Highly Cited
1999
Highly Cited
1999
Neural stem cells reside in the subventricular zone (SVZ) of the adult mammalian brain. This germinal region, which continually… Expand
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Highly Cited
1999
Highly Cited
1999
Neuronal precursors reside in the subventricular zone (SVZ) of adult mammals. This region is composed of a network of chains of… Expand
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Highly Cited
1997
Highly Cited
1997
Cyclin-dependent kinases (cdk) play an essential role in the intracellular control of the cell division cycle (cdc). These… Expand
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Highly Cited
1993
Highly Cited
1993
Taxol inhibited HeLa cell proliferation by inducing a sustained mitotic block at the metaphase/anaphase boundary. Half-maximal… Expand
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Highly Cited
1987
Highly Cited
1987
The subcellular distribution of microtubules containing acetylated alpha-tubulin in mammalian cells in culture was analyzed with… Expand
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Highly Cited
1986
Highly Cited
1986
In the fission yeast S. pombe the cdc25+ gene function is required to initiate mitosis. We have cloned the cdc25+ gene and have… Expand
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Highly Cited
1980
Highly Cited
1980
Abstract The distribution of peptide-containing neurons in the oesophagus, stomach and small and large intestine of the rat and… Expand
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Highly Cited
1967
Highly Cited
1967
The majority of the colchicine-3H bound by tissue culture cells (KB or Hela) was found to be present as a noncovalent complex… Expand
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