Taxanes

Known as: Taxane Compound, taxane 
A type of drug that blocks cell growth by stopping mitosis (cell division). Taxanes interfere with microtubules (cellular structures that help move… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Vinca alkaloids have been approved as anticancer drugs for more than 50 years. They have been classified as cytotoxic… (More)
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Review
2017
Review
2017
INTRODUCTION Anti-HER2 targeted therapy is one of the key advances in the treatment of breast cancer that have occurred in the… (More)
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Highly Cited
2015
Highly Cited
2015
IMPORTANCE We previously showed that detection of androgen receptor splice variant 7 (AR-V7) in circulating tumor cells (CTCs… (More)
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Highly Cited
2011
Highly Cited
2011
CONTEXT Prediction of high probability of survival from standard cancer treatments is fundamental for individualized cancer… (More)
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Highly Cited
2008
Highly Cited
2008
  • Eva S. Thomas
  • Journal of clinical oncology : official journal…
  • 2008
TO THE EDITOR: On behalf of the study investigators, I would like to communicate results of a US Food and Drug Administration… (More)
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Review
2004
Review
2004
Taxanes are one of the most powerful classes of compounds among all chemotherapeutic drugs. Only 30 years separate the isolation… (More)
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Review
2000
Review
2000
The taxanes are anticancer cytotoxics that stabilise cellular microtubules. Two members, paclitaxel and docetaxel have… (More)
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Highly Cited
2000
Highly Cited
2000
The epothilones are naturally occurring antimitotic drugs that share with the taxanes a similar mechanism of action without… (More)
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Highly Cited
1999
Highly Cited
1999
Elevated tumor interstitial fluid pressure (IFP) is partly responsible for the poor penetration and distribution of therapeutic… (More)
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Highly Cited
1993
Highly Cited
1993
Taxomyces andreanae, a fungal endophyte, was isolated from the phloem (inner bark) of the Pacific yew, Taxus brevifolia. The… (More)
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