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Taxoids

Known as: Taxoids [Chemical/Ingredient], taxoid 
A group of diterpenoid CYCLODECANES named for the taxanes that were discovered in the TAXUS tree. The action on MICROTUBULES has made some of them… 
National Institutes of Health

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Narrower (46)

1,7-dihydroxytaxinine1-deoxybaccatin VI10-deacetylpaclitaxel10-deacetyltaxinine
In Bloodagonistsantagonists & inhibitorschemical synthesis

Papers overview

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Review
2005
Review
2005
Anti-tumour activity of zoledronic acid.
Review
2001
Review
2001
General and recent aspects of the chemistry and structure-activity relationships of taxoids.
The antimitotic agents of the Taxoid series are important substances as anticancer drugs. The efficacy of paclitaxel (Taxol) and… 
Highly Cited
2001
Highly Cited
2001
A phase II study of pemetrexed disodium (LY231514) in patients with locally recurrent or metastatic breast cancer.
Review
2001
Review
2001
Chemistry and chemical biology of taxane anticancer agents.
Taxol (paclitaxel) and Taxotere (docetaxel) are currently considered to be among the most important anticancer drugs in cancer… 
2001
2001
Centrosome and spindle pole microtubules are main targets of a fluorescent taxoid inducing cell death.
Microtubules offer a very large local concentration of binding sites for cytotoxic taxoids or for hypothetical endogenous… 
1998
1998
Taxoids in combination with anthracyclines and other agents: pharmacokinetic considerations.
The combination in clinical trials of taxoids with doxorubicin has focused attention on possible drug interactions. One specific… 
Review
1996
Review
1996
Taxus sp. cell, tissue and organ cultures as alternative sources for taxoids production: a literature survey
The literature concerning the tissue culture of Taxus sp. as an alternative source for taxoid production is reviewed. The aim of… 
1996
1996
Structural requirements of taxoids for nitric oxide and tumor necrosis factor production by murine macrophages.
Taxol (paclitaxel), a microtubule stabilizer with antitumor activity, mimics the actions of lipopolysaccharide (LPS) on murine… 
Review
1995
Review
1995
Clinical drug resistance: the role of factors other than P-glycoprotein.
1994
1994
Predominant labeling of beta- over alpha-tubulin from porcine brain by a photoactivatable taxoid derivative.
An [(azidophenyl)ureido]taxoid (TaxAPU) was synthesized in a radiolabeled form by coupling an aminotaxoid to tritiated N-methyl-N… 
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