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Diterpenoids from Isodon species and their biological activities.
Isodon species (Labiatae) are widely distributed plants, many of which are used in folk medicine, and have received considerable phytochemical and biological attention over the past twenty years. Expand
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells.
Adenanthin can serve as what is to the authors' knowledge the first lead natural compound for the development of Prx I- and Prx II-targeted therapeutic agents, which may represent a promising approach to inducing differentiation of APL cells. Expand
Kadcoccilactones A-J, triterpenoids from Kadsura coccinea.
This is the first report on nortriterpenoids (2, 4-6, 8-10) from the genus Kadsura, and the structures were elucidated by spectroscopic evidence and single-crystal X-ray diffraction analysis. Expand
Compounds from Kadsura heteroclita and related anti-HIV activity.
Phytochemical investigation of the stems of Kadsura heteroclita led to isolation of 16 compounds, including the triterpenoid named longipedlactone J (2), and two dibenzocyclooctadiene type lignansExpand
Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer
It is found that a natural compound, rabdocoetsin B which is extracted from a Traditional Chinese Medicinal herb Rabdosia coetsa, could induce down-regulation of CIP2A and inactivation of Akt pathway, and inhibit proliferation and induce apoptosis in a variety of lung cancer cells. Expand
Nortriterpenoids and lignans from Schisandra sphenanthera.
Nortriterpenoids, sphenadilactone C (1) and sphenasin A (2), together with four known lignans (3-6), were isolated from the leaves and stems of Schisandra sphenanthera and showed weak anti-HIV-1 activity. Expand
Lignans from Kadsura angustifolia.
Phytochemical investigation of Kadsura angustifolia led to the isolation and identification of 26 lignans and two triterpenoids, including 11 new lignan named kadangustins A-K ( 1- 11), which were elucidated by analysis of spectroscopic data. Expand
Dibenzocyclooctadiene lignans from Schisandra wilsoniana and their anti-HIV-1 activities.
Twelve new dibenzocyclooctadiene lignans, marlignans A-L (1-L), together with 16 known compounds, were isolated from the leaves and stems of Schisandra wilsoniana for their anti-HIV activities. Expand
Phytochemistry and pharmacology of the genus Leonurus: The herb to benefit the mothers and more.
Anti-inflammation is the major bioactivity discovered so far for the labdane diterpenoids from the genus Leonurus, whose further therapeutic potential still remains for exploration. Expand
Kadpolysperins A–N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma
Fourteen new lanostane triterpene acids (1-14), and five known analogues (15-19) were isolated from the stems of Kadsura polysperma. Compound 1, with a rearranged tetracyclic skeleton, is anExpand