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Variation of free phenolic acids in medicinal plants belonging to the Lamiaceae family.
- G. Zgórka, K. Głowniak
- Medicine, Chemistry
- Journal of pharmaceutical and biomedical analysis
- 1 August 2001
Ten species belonging to the family Lamiaceae and representing the most popular medicinal plants used in Polish phytotherapy were examined for the content of free phenolic acids, determined by the rapid, selective and accurate method combining solid-phase extraction and high-performance liquid chromatography. Expand
Imperatorin enhances the protective activity of conventional antiepileptic drugs against maximal electroshock-induced seizures in mice.
- J. Luszczki, K. Głowniak, S. Czuczwar
- Chemistry, Medicine
- European journal of pharmacology
- 28 November 2007
It is demonstrated that imperatorin enhanced the antiseizure effects of carbamazepine, phenobarbital and phenytoin in the mouse maximal electroshock seizure model. Expand
Time–course and dose–response relationships of imperatorin in the mouse maximal electroshock seizure threshold model
It is concluded that imperatorin produces the anticonvulsant effect in the maximal electroshock seizure threshold test in a dose-dependent manner. Expand
Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: A comparative study
Both natural coumarin derivatives deserve more attention from a preclinical point of view as compounds possessing some potentially favorable activities in terms of suppression of seizures, quite similar to those reported for valproate. Expand
Solid-phase extraction and reversed-phase high-performance liquid chromatography of free phenolic acids in some Echinacea species
A new method is described combining solid-phase extraction (SPE) and reversed-phase high-performance liquid chromatography (RP-HPLC) for the isolation, purification as well as qualitative and… Expand
Solid-liquid extraction and cation-exchange solid-phase extraction using a mixed-mode polymeric sorbent of Datura and related alkaloids.
Tropane alkaloids solid-liquid extraction methods were developed and comprised ambient pressure ones: extraction with hot solvent, extraction at room temperature, on ultrasonic bath as well as… Expand
Coumarins from Angelica Lucida L. - Antibacterial Activities
The first phytochemical investigation of the fruits of Angelica lucida has led to the isolation and characterization of five known coumarins (imperatorin, isoimperators, heraclenol, oxypeucedanin hydrate and heracLenin), exhibiting an interesting antimicrobial profile. Expand
Antimicrobial efficacy of Mutellina purpurea essential oil and α-pinene against Staphylococcus epidermidis grown in planktonic and biofilm cultures
Investigation of the antimicrobial efficacy of Mutellina purpurea essential oil and α-pinene against planktonic and biofilm cultures of S. epidermidis ATCC 35984 and S. 37IINL found the lowest EO concentration completely inhibiting the biofilm formation was 0.625 mg/mL; α-pinsene caused the same result at a slightly higher concentration with MBIC = 1.25 mg/mL. Expand
Establishment of a co-culture of Ammi majus L. and Ruta graveolens L. for the synthesis of furanocoumarins
- M. Sidwa-Gorycka, A. Królicka, M. Kozyra, K. Głowniak, F. Bourgaud, E. Łojkowska
- 1 December 2003
Two systems of co-cultivation were tested, namely to test different tissues inoculation ratios as well as the influence of the photoperiod and darkness conditions on A. majus and R. graveolens tissues growth and the accumulation of secondary metabolites. Expand
A Comparison of Methodical Approaches to Fingerprinting of the Volatile Fraction from Winter Savory (Satureja montana)
It was the aim of this study to compare the efficiency of the different essential oil extraction methods upon the two winter savory (Satureja montana) samples of different origin. The compared… Expand