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Experimental and clinical evidence support the role of inflammation in atherosclerosis and its complications… Expand Microtubules are cytoskeletal polymers of tubulin involved in many cellular functions. Their dynamic instability is controlled by… Expand BACKGROUND
Primary systemic amyloidosis is an uncommon disease characterized by the accumulation in vital organs of a fibrillar… Expand Intrinsic and acquired multidrug resistance (MDR) is an important problem in cancer therapy. MDR in human KB carcinoma cells… Expand To determine whether colchicine prevents or ameliorates amyloidosis in patients with familial Mediterranean fever, we followed… Expand This experiment examines the notion that in the rat the hippocampal formation is an essential structure in the neurological… Expand TAXOL (Fig. 1) was isolated from the plant Taxus brevifolia (western yew) by Wani et al., who reported that the molecule has… Expand Chinese hamster ovary cells selected for resistance to colchicine display pleiotropic cross-resistance to a wide range of… Expand The majority of the colchicine-3H bound by tissue culture cells (KB or Hela) was found to be present as a noncovalent complex… Expand The method was developed for bone marrow of mice but is applicable to other tissues and other species of small mammals. Mice are… Expand