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The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis.
The studies demonstrate that the molecular mechanisms that regulate hematopoietic and vasculogenic cells in normal zebrafish have been conserved throughout vertebrate evolution and the clo and spt genes are key regulators of these programs.
Intraembryonic hematopoietic cell migration during vertebrate development.
Findings support a hypothesis in which the hematopoietic program of vertebrates is established by variations in homologous migration pathways of extra- and intraembryonic progenitors.
Solar UVB-induced DNA damage and photoenzymatic DNA repair in antarctic zooplankton.
- K. D. Malloy, M. A. Holman, D. Mitchell, H. Detrich
- Environmental ScienceProceedings of the National Academy of Sciences…
- 18 February 1997
It is suggested that increased solar UV may reduce recruitment and adversely affect trophic transfer of productivity by affecting heterotrophic species as well as primary producers.
Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages.
Results show that cloche is involved in the genesis and early diversification of the endothelial and blood lineages, possibly by affecting a common progenitor cell population.
Towards complete and error-free genome assemblies of all vertebrate species
The Vertebrate Genomes Project is embarked on, an effort to generate high-quality, complete reference genomes for all ~70,000 extant vertebrate species and help enable a new era of discovery across the life sciences.
A Model for Cleavage Plane Determination in Early Amphibian and Fish Embryos
Genomic remnants of alpha-globin genes in the hemoglobinless antarctic icefishes.
- E. Cocca, M. Ratnayake-Lecamwasam, H. Detrich
- BiologyProceedings of the National Academy of Sciences…
- 14 March 1995
It is proposed that the hemoglobinless phenotype of extant icefishes is the result of deletion of the single adult beta-globin locus prior to the diversification of the clade.
A genomic fossil reveals key steps in hemoglobin loss by the antarctic icefishes.
Surprisingly, a phylogenetically derived icefish species, Neopagetopsis ionah, possesses a complete, but nonfunctional, adult alphabeta-globin complex, which is concluded to be a "genomic fossil" that reveals key intermediate steps on the pathway to loss of hemoglobin expression by all ice fish species.
Unexpected beta2-microglobulin sequence diversity in individual rainbow trout.
Variation in the beta2m cDNA sequences is mainly at sites that do not perturb the structure of the maturebeta2m protein, showing that the observed diversity of the trout beta2M genes is not primarily a result of pathogen selection.
Molecular and morphological phylogenies of the Antarctic teleostean family Nototheniidae, with emphasis on the Trematominae
- S. Sanchez, A. Dettaï, C. Bonillo, C. ozouF-cosTaz, H. Detrich, G. Lecointre
- BiologyPolar Biology
Four independent molecular data sets were sequenced in order to solve longstanding phylogenetic problems among Antarctic teleosts of the family Nototheniidae and show that the tendencies shown by some trematomines to secondarily colonize the water column are not gained through common ancestry.