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BACKGROUND & AIMS
It is important to determine whether infliximab therapy can be safely interrupted in patients with Crohn's… Expand This paper is the second in a series of three publications relating to the European evidence-based consensus on the diagnosis and… Expand Inhibition of cellular replication is one characteristic of cancer cells that has been effectively exploited in the past for the… Expand Drug treatment of colorectal cancer has made impressive progress during the past 10 years. In addition to the traditional 5… Expand Most current chemotherapy regimens for cancer consist of empirically designed combinations, based on efficacy and lack of… Expand We have examined the effects of commonly used chemotherapeutic agents on human colon cancer cell lines in which the p53 pathway… Expand BACKGROUND
Brain tumours rarely occur in survivors of childhood acute lymphoblastic leukaemia after cranial radiotherapy. An… Expand In the present study, we report the characterization of the p53 tumor suppressor pathway in the 60 cell lines of the National… Expand Clinical features and specific aspects of treatment were evaluated in 612 patients with gram-negative bacteremia observed over a… Expand 1. A new antimetabolite, 6-mercaptopurine, has been shown to produce good clinical and hematologic remissions in fifteen out of… Expand