razoxane

Known as: 2,6-Piperazinedione, 4,4'-(1-methyl-1,2-ethanediyl)bis-, (+-)-, Razoxane [Chemical/Ingredient] 
An orally bioavailable bis-dioxopiperazine and a derivative of the chelating agent ethylenediaminetetraacetic acid (EDTA) with antineoplastic… (More)
National Institutes of Health

Papers overview

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2006
2006
BACKGROUND Chondrosarcomas and chordomas are reported to have low radio-sensitivity. Therefore, a study was undertaken to explore… (More)
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2003
2003
To evaluate the local effect of conventional photon irradiation in chordomas if the radiosensitizing agent razoxane is added. The… (More)
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2003
2003
Measurement of tumour and normal tissue perfusion in vivo in cancer patients will aid the clinical development of antiangiogenic… (More)
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2000
2000
Renal cell carcinoma (RCC) is an angiogenic tumor resistant to standard cytotoxic chemotherapeutic agents. Although often… (More)
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1994
1994
PURPOSE The effect of the sensitizer razoxane was prospectively evaluated in recurrent rectal cancer. Endpoints of the study were… (More)
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Review
1991
Review
1991
Razoxane blocks cell division in the G2/M phase of the cell generation cycle and appears to normalize tumour neovasculature… (More)
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1991
1991
The effects of conventional vs protected housing, and those caused by the periodic application of a psychological Stressor… (More)
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1987
1987
The cytostatic and antimetastatic activities of 1,2-di(3,5-dioxopiperazin-1-yl) propane (ICRF-159, razoxane) were studied in a… (More)
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1985
1985
Two new cases of acute myeloid leukaemia occurring after razoxane therapy are recorded and further haematological and cytogenetic… (More)
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1981
1981
A single dose of 200 mg/kg razoxane protected mice against the subchronic lethal effects (i.e. within 21 days) of 10 mg/kg… (More)
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