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Dexrazoxane hydrochloride

Known as: Hydrochloride, Dexrazoxane, Razoxane, (S)-Isomer, Hydrochloride 
A drug used to treat severe side effects caused by certain anticancer drugs. It is used under the brand name Totect to treat the toxic effects of an… 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Although chemotherapy has improved outcome of osteosarcoma, 30–40% of patients succumb to this disease. Survivors experience… 
Highly Cited
2014
Highly Cited
2014
BackgroundThe bisdioxopiperazine dexrazoxane (DRZ) prevents anthracycline-induced heart failure, but its clinical use is limited… 
2010
2010
OBJECTIVE: To describe a successful case of dexrazoxane treatment after an extravasation of doxorubicin and share a creative… 
Review
2008
Review
2008
Management of anthracycline extravasation is problematic and most reports are anecdotal. On September 6, 2007, the U.S. Food and… 
2004
2004
The present study investigates the immunological effects of a combination treatment of mitoxantrone and the cardioprotector… 
Review
1998
Review
1998
The bisdioxopiperazine dexrazoxane (ICRF-187) has proven to be clinically very effective in reducing the cardiotoxicity of… 
1997
1997
The antitumor drug mitindomide (NSC 284356) was shown to inhibit the decatenation activity of human and Chinese hamster ovary…